近视LASIK手术后高阶像差的改变  

Changes of higher-order aberrations after LASIK surgery for myopia.

作　　者：何异[1] 刘谊[1] 唐晓昭[2] 廖志强[2] 刘京珍[2] 

机构地区：[1]四川大学华西医院眼科,四川成都610041 [2]成都市第三人民医院眼科,四川成都610031

出　　处：《眼外伤职业眼病杂志》2006年第3期178-181,共4页Journal of Injuries and Occupational Diseases of the Eye with Ophthalmic Surgeries

摘　　要：目的分析LASIK手术对高阶像差的影响,分析LASIK术前近视屈光度与LASIK术后眼的高阶像差的关系。方法采用WASCA波前像差仪测量150眼LASIK术前及术后1月及3月瞳孔直径分别为小瞳孔(3 mm)及大瞳孔(6.25 mm)时的总高阶像差的均方根及第三和第四阶像差的Zernike系数,并计算出球差、慧差、第三及第四阶像差的均方根。对结果进行方差分析和直线相关分析。结果LASIK术后,大瞳孔直径和小瞳孔直径下高阶像差均明显增高。无论瞳孔大小,术后3月较1月时高阶像差均轻微下降。大瞳孔直径下,光区直径为6.25 mm时,术后球差、第四阶像差和总高阶像差与术前屈光度存在正相关。结论LASIK术后,高阶像差明显增高,尤以球差最明显。术前屈光度越高,手术所导致的高阶像差也越大,屈光度过高的近视眼不宜采用波前像差引导的个体化屈光手术。Objective To investigate the influence of LASIK surgery on the higher-order aberrations for myopia and analyze the relationship between the higher-order aberrations after LASIK surgery and the myopic diopters before LASIK surgery. Methods The RMS value of the total higher-order aberrations and the Zernike coefficients of the 3rd and the 4th higher-order aberrations in 150 eyes were measured in small pupil（3 mm） and large pupil（6.25 mm） by WASCA aberrometer preoperatively, 1 month and 3 mouths postoperatively. The RMS value of spherical aberration,coma,the 3rd and 4th higher-order aberrations were calculated. ANOVA , and the linear Correlation were used to analyze the data, Results After LASIK,the higher-order aberrations increased significantly for both small and large pupil. The higher-order aberrations 3 months after LASIK regressed slightly compared with the higher-order aberrations 1 month after LASIK at both small and large pupil. At large pupil, the spherical aberration, the 4th order higher-order aberration and the total higher-order aberrations after LASIK had significant positive correlation with myopic diopters before LASIK when the optical zone diameter was 6.25 mm. Conclusions After LASIK, the higher-order aberrations increase significantly, especially for spherical aberration, The higher-order aberrations after LASIK surgery have positive correlation with the myopie diopters before LASIK. For wavefront-guided refractive surgery,the myopic, diopters before refractive surgery should not be too high.

关 键 词：LASIK 波前像差 近视 

分 类 号：R779.63[医药卫生—眼科]