L-鸟氨酸发酵培养基的中心复合法优化  

Optimization of the Medium for L-ornithine Fermentation Using Central Composite Design

作　　者：万红贵[1] 叶慧[1] 陆彬[1] 王涛[1] 朱庆平[1] 

机构地区：[1]南京工业大学制药与生命科学学院

出　　处：《食品与发酵工业》2006年第1期37-40,共4页Food and Fermentation Industries

摘　　要：考察不同碳氮源对Corynebacterium glutamicum1006发酵产L-鸟氨酸的影响,并借助于statistica6.0数学分析软件,采用Plackett-Burman试验设计及中心复合试验设计分析法,对L-鸟氨酸产生菌1006进行了发酵培养基的优化研究。优化后的发酵培养基使1006菌株的L-鸟氨酸产率提高了44.03%。The effects of different carbon sources and nitrogen sources on the fermentation of L -ornithine were investigated. The static culture media of Corynebacteriurn glutarnicum 1006 producing L -ornithine was optimized using Statistic 6.0 software combined with the Plackett-Burman design and central composite design method. It is found that the L -ornithine yield with Corynebacterium glutaramicuum 1006 was increased by 44.03 % using the optimized medium.

关 键 词：L-鸟氨酸 发酵 Plackett—Burman 中心复合设计 

分 类 号：TQ922[轻工技术与工程—发酵工程]