酵母海藻糖的代谢与调控研究进展  

Advanced in Metabolism and Regulation of Trehalose in Yeast

作　　者：池振明[1] 梁丽琨[1] 朱开玲[1] 张风丽[1] 

机构地区：[1]中国海洋大学联合国教科文组织海洋生物中心,山东青岛266003

出　　处：《中国海洋大学学报（自然科学版）》2006年第2期209-214,共6页Periodical of Ocean University of China

基　　金：国家自然科学基金项目(30370015)资助

摘　　要：海藻糖(Trehalose)是化学性质稳定的非还原性二糖,由2个吡喃葡萄糖分子通过α-1,1-糖苷键连接而成,海藻糖独特的物理特性使其在细胞中可起到稳定生物大分子的作用,因而在化妆品、医药和食品等工业领域中有极好的应用前景。在酵母菌中海藻糖可作为储藏碳水化合物和细胞应激反应保护剂。当环境条件变化时细胞内海藻糖含量会发生显著变化,而海藻糖的积累已被证实在不同胁迫应答中起关键作用,海藻糖代谢途径仅有几个代谢物组成,却受到复杂的代谢调控机制的控制。此外,海藻糖代谢在酵母菌的糖代谢中还起了非常重要的调控作用。Trehalose plays an important in food manufacture, vaccine protection, role in cell survival under adverse conditions and has many applications pharmaceuticals, and cosmetic products. The trehalose cycle in yeast consists of a small number of metabolites, which affect each other through a surprising number of control signals. The signals aid the cell in a complex decision on responses to different external conditions. It is showed that trehalose metabolism is also important for the control of glucose influx during the cellular response to adverse conditions.

关 键 词：海藻糖 代谢 调控 酵母菌 

分 类 号：Q939[生物学—微生物学]