蕈样肉芽肿病伴口周及黏膜明显受累  

Mycosis fungoides with predominant periorificial and mucous involvement (Fren)

作　　者：Dereure O. Guilhou J.-J. 周少娜 

机构地区：[1]Service de Dermatologie, Hpital Saint-loi, 80, avenue Augustin Fliche, 34295 Montpellier Cedex 5

出　　处：《世界核心医学期刊文摘（皮肤病学分册）》2006年第3期22-23,共2页Digest of the World Core Medical JOurnals:Dermatology

摘　　要：Introduction. Specific involvement of the mucous membranes is possible during the course of mycosis fungoides but has seldom been reported, except in postmortem series. A single mucous membrane is most often involved, mainly in themouth. Such mucous lesions are generally ominous with regard to the general outcome of the disease. Observation. A 74 year-old woman was investigated for mycosis fungoides complicated with lesions around the mouth and of the mucosa, involving the tongue and esophagus, featuring ulcerated nodules with specific chorion infiltration and epidermotropism. This progression was rapidly followed by a fatal outcome, in spite of various systemic treatments. Discussion. This case report of mycosis fungoides displaying multiple and predominant oral and mucosal involvement of mycosis fungoides is unique. The rapidly unfavorable outcome confirms the ominous prognosis of mucous lesions, whereas no patent visceral extension was detected. The mechanisms underlying the mucous membranes involvement is discussed.Introduction. Specific involvement of the mucous membranes is possible during the course of mycosis fungoides but has seldom been reported, except in postmortem series. A single mucous membrane is most often involved, mainly in themouth. Such mucous lesions are generally ominous with regard to the general outcome of the disease. Observation. A 74 year-old woman was investigated for mycosis mouth fungoides complicated with lesions around the and of the mucosa, involving the tongue and esophagus featuring ulcerated nodules with specific chorion infiltration and epidermotropism. This progression was rapidly followed by a fatal outcome, in spite of various systemic treatments. Discussion. This case report of mycosis fungoides displaying multiple and predominant oral and mucosal involvement of mycosis fungoides is unique.

关 键 词：蕈样肉芽肿 黏膜损害 肉芽肿病 口腔黏膜 系统性治疗 预后不良 女性患者 口周皮肤 向表皮性 浆膜浸润 

分 类 号：R739.5[医药卫生—肿瘤] R733.1[医药卫生—临床医学]