生物能量在生命体中传递的新理论及实验证实  

The New Theory of Bio-energy Transport in Living Systems and Its Verification of Experiments

作　　者：庞小峰[1] 

机构地区：[1]电子科技大学生命科学技术学院,生物物理与生物电子重点实验室,成都610054

出　　处：《世界科技研究与发展》2006年第2期1-6,41,共7页World Sci-Tech R&D

摘　　要：我们从蛋白质的分子结构和ATP水解所放出能量的特征出发,提出了一个新的生物能量传递理论。并用新的哈密顿函数和波函数代替了原来旧的函数,用解析的方法求出了传递生物能量的孤子在其生理温度和它的寿命时间内能够传递过上千个氨基酸分子,于是它可能是传递生物能量的真正载流子。用解析和数值模拟的方法研究了这种传递生物能量孤子的特性和在生理温度300K时的热力学稳定性,证明了这种孤子在生理温度时是十分稳定的,它的寿命能达到300ps,可能是生物能量的传递者。再通过实验测定了在胶原蛋白和牛血清蛋白等(-螺旋蛋白的光谱特性及其在27-95℃范围内其谱线分布和谱线强度随温度的变化,把所检测的三个结果与能量传递的理论预示的结果相比较,发现它们完全一致,从而从实验上证明了在蛋白质分子中建立的生物能量传递理论是正确的。而理论预示的孤子是蛋白质当中生物能量传递的真正载流子。As is known, the bio-energy transport in the living systems is a basic problem for the life science. It is related to transport of the energy released in APT hydrolysis along the protein molecules, and is determined by dynamic properties of the protein molecules. According to the distribution of ATP molecules and its features of hydrolysis and structure properties of protein molecules we proposed a new theory of bio-energy transport in protein molecules based on Davydov model. In this new model we represented the collective excitation of vibrational quanta of amide-I by a two-quantum quasicoherent wave function, both displacement of amino acid residues arising from the vibration of amide-Is and relative displacement of neighboring amino acids caused by resonant interaction between neighboring amides were taken into account in the new Hamiltonian. The lifetime of the new soliton transported the bio-energy obtained from this theory is about 10- 10 second, in this time the soliton can move over more than one thousand of amino acid residues. This shows that the soliton is possibly a cartier of the bio-energy transport, and can play an important role in biological processes. The results obtained from this theory have been verified by numerical simulation obtained from fourth-order-Runge-Kutta method and by three experimental data of infrared absorption of collagen by us. Therefore, this theory is correct, available and valuable in biology.

关 键 词：生物能量 蛋白质 孤子 红外吸收光谱 RUNGE-KUTTA法 实验证实 

分 类 号：Q591.8[生物学—生物化学]