基于多agent系统的细菌趋药性仿真  

The MAS-based Simulation of Bacterial Chemotaxis

作　　者：刘俊[1] 郑浩然[1] 钮俊清[1] 

机构地区：[1]中国科学技术大学计算机科学技术系,安徽合肥230027

出　　处：《计算机仿真》2006年第4期138-140,共3页Computer Simulation

基　　金：中国科学技术大学高水平大学建设重点项目;中国科学技术大学青年基金项目

摘　　要：细菌(如大肠杆菌)趋药性现象是细胞信号转导研究的典型案例,该文在阐述细菌趋药性现象的生物过程和研究进展的基础上,针对当前计算机仿真方法的不足之处,提出了一种基于多agent技术的计算机仿真方法,包括设计了针对细胞信号转导现象的仿真框架和基于反应式agent结构和多线程技术的实现流程。最后,在仿真框架的基础上设计了细菌趋药性中的趋药性与自适应现象的仿真实验,实验结果表明此方法较现有方法有良好的特性,在生物系统仿真中具有广泛的应用前景。Bacterial chemotaxis, such as Escherichia coli, is a typical case in signal transduction study. Acording to the biological phenomena and research progress of bacterial chemotaxis, the approach of MAS - based simulation of bacterial chemotaxis is presented in this paper by comparing with current approaches. The MAS - based simulation includes the simulation framework for signal transduction phenomena and the implementation process based on feedback agent stucture and multi - thread technology. At last an experiment for bacterial chemotaxis phenomena is designed based on the simulation framework, and the experiment result shows that this approach has good characteristics and broad application prospects in biological system simulations.

关 键 词：细胞信号转导 系统生物学 细菌趋药性 多艾真特系统 仿真 

分 类 号：TP391.9[自动化与计算机技术—计算机应用技术]