异常的口腔血管网模式:唐氏综合征的一种新的临床征象  

Abnormal oral vascular network pattern geometry: A new clinical sign of Down syndrome

作　　者：Latini G. Bianciardi G. Parrini S. 贺莉 

机构地区：[1]Division of Neonatology, Ospedale A. Perrino, S. S. 7 per Mesagne, 72100 Brindisi, Italy,Dr

出　　处：《世界核心医学期刊文摘（儿科学分册）》2006年第5期32-32,共1页

摘　　要：Down syndrome is a leading genetic cause of mental retardation. Here, we show high fractal dimensions and Lempel-Ziv complexity and lower minimum path fractal dimension (P ≤.0006) for the oral vascular networks of patients (n = 14)-and their unaffected parents. This newly rec- ognized sign may provide a useful phenotypical marker for identifying couples potentially at risk for offspring with Down syndrome.Down syndrome is a leading genetic cause of mental retardation. Here, we show high fractal dimensions and Lempel-Ziv complexity and lower minimum path fractal dimension （P ≤ . 0006） for the oral vascular networks of patients （n = 14） - and their unaffected parents. This newly recognized sign may provide a useful phenotypical marker for identifying couples potentially at risk for offspring with Down syndrome.

关 键 词：唐氏综合征 血管网 临床征象 口腔异常 精神发育迟滞 遗传原因 复杂性 标记物 新征象 

分 类 号：R749.94[医药卫生—神经病学与精神病学] R622.1[医药卫生—临床医学]