贝沙罗汀治疗Sézary综合征过程中伴发肉芽肿皮损  

Sézary syndrome associated with granulomatous lesions during treatment with bexarotene

作　　者：Ruiz-De-Casas A. Carrizosa-Esquivel A. Herrera-Saval A. 罗素菊 

机构地区：[1]Department of Dermatology, Virgen Macarena University Hospital, Seville, Spain Dr.

出　　处：《世界核心医学期刊文摘（皮肤病学分册）》2006年第6期35-35,共1页Digest of the World Core Medical JOurnals:Dermatology

摘　　要：Sézary syndrome (SS) is a leukaemic variant of cutaneous T-cell lymphoma (CTCL). We report a patient with SS who developed granulomatous lesions. These lesions broke out during treatment with bexarotene when the disease had appeared to stabilize. After a partial clinical remission the disease showed rapid progression and finally led to the patient’s death. This contradicts the initial assessment, which considered the granulomatous inflammation as a good prognostic factor in CTCL.Sézary syndrome （SS） is a leukaemic variant of cutaneous T-cell lymphoma （CTCL）. We report a patient with SS who developed granulomatous lesions. These lesions broke out during treatment with bexarotene when the disease had appeared to stabilize. After a partial clinical remission the disease showed rapid progression and finally led to the patient＇s death. This contradicts the initial assessment, which considered the granulomatous inflammation as a good prognostic factor in CTCL.

关 键 词：肉芽肿性炎症 综合征 皮损 治疗 皮肤T细胞淋巴瘤 伴发 临床症状 预后因子 CTCL 患者 

分 类 号：R777.4[医药卫生—眼科] R758.63[医药卫生—临床医学]