近视屈光参差眼的角膜地形图和生物超声测定的分析  

Analysis of corneal topography and ocular biometry in myopic anisometropia eyes

作　　者：王海英[1] 赵堪兴[1] 高雅萍[2] 崔丽红[1] 王立书[2] 

机构地区：[1]天津眼科医院,天津市天津职业大学300020 [2]天津职业大学,天津市300402

出　　处：《眼科新进展》2006年第11期841-844,共4页Recent Advances in Ophthalmology

摘　　要：目的 通过生物学测量了解屈光参差的发生机理，并探讨在基因相同的情况下近视的发生与发展。方法 样本来自我院验光配镜中心、准分子手术治疗中心的70名屈光参差患者（双眼等效球镜差≥1．0D），年龄18～42岁；同期选取35名双眼等效球镜差＜1．0D的患者作为对照组。在征得本人同意的情况下，对其进行屈光检查及各生物学因子的测定。统计处理采用方差分析及配对t检验。结果 随着屈光参差度的增加，双眼的角膜中央最大屈光力差、角膜中央最小屈光力差及角膜中央平均屈光力差基本相同，差异无统计学意义（P＞0.05）；随着屈光参差度的增加，双眼的眼轴长度差由对照组的0．10mm上升至1．21mm；玻璃体腔径差分别为0．10mm，0．64mm及1．19mm；眼轴／曲率差分别为0．00mm，0．01mm及0．02mm，呈现逐渐增加的趋势，差异有统计学意义（P＜0．001）。结论 屈光参差与眼轴发育不平衡有关，与角膜屈光力无关；在相同的基因下，近视的进展主要为玻璃体腔径的增长而引起的眼轴增长。Objective To investigate the mechanism of anisometropia occurrence and to study the genesis and development of anisometropia under the same gene by ocular biometry. Methods Seventy subjects who suffered anisometropia （≥1.0 D） and were aged 18～42 years were randomly selected, 35 subjects without anisometropia （〈1.0 D） were recruited for the control group. For each subject refractive error and ocular biometry were measured respectively. Results The differences of keratometer value in steep meridian, keratometer value in flat meridian, average keratometer value for two eyes were almost the same between different groups（P〉0.05）;The difference of axial length was 0.10 mm, 0.64 mm and 1.21 mm respectively, vitreous length was 0.10 mm,0.64 mm and 1.19 mm,and axial length/ average keratometer value was 0.00 mm, 0.01 mm and 0.02 mm in three groups, increasing with the severity of anisometropia（P〈0. 001 ）. Conclusion The origin of the anisometropia is involved with imbalanced development of axial and independent of dioptric power. Under the same gene, the development of myopia is reason of the growth of axis oculi induced by increased vitreous length.

关 键 词：屈光参差 近视 眼球生物学测量 

分 类 号：R778.11[医药卫生—眼科]