北京市医疗保险住院患者醒脑静注射液应用情况调查与分析  

Use of Xingnaojing Injection in Medical Insurance Inpatients in Beijing:Survey and Analysis

作　　者：刘芳[1] 赵荣生[1] 李静[2] 李培红[3] 李志琴[4] 张宁 王汝龙 李大魁 薛立宁 严静敏[7] 

机构地区：[1]北京大学第三医院,北京市100083 [2]北京市煤炭总医院,北京市100062 [3]北京市西苑医院,北京市100091 [4]北京市和平里医院,北京市100013 [5]北京市崇文中医院,北京市100062 [6]北京药学会,北京市100027 [7]北京市医疗保险事务管理中心,北京市100050

出　　处：《中国药房》2007年第2期85-88,共4页China Pharmacy

摘　　要：目的:评价北京市“医保”住院患者醒脑静注射液的应用状况,为合理用药和“医保”支付提供参考。方法:随机抽取2004年北京市医疗保险信息数据库中5家不同级别医院应用醒脑静的住院病例,调查其适应证、剂量、疗程、不良反应等。结果:共调查病例676例,应用醒脑静的前10种适应证中18．0％与药品说明书不符,17．5％缺乏临床研究证据支持;平均单次剂量为(27．9±9．0)mL,高于药品说明书规定的常用量和临床研究中的常用量;平均疗程14．6d,有20．9％超过20d;合并用药有抗栓药(13．3％)、活血化淤中药(12．7%)等。结论:“医保”患者醒脑静注射液应用存在与药品说明书规定的适应证、给药剂量及现有临床研究证据不符的情况。OBJECTIVE： To evaluate the use of Xingnaojing Injection in medical insurance inpatients in Beijing city so as to provide reference for rational drug use and medical insurance billing .METHODS： Inpatient cases using Xingnaojing Injection in 5 Beijing hospitals of different levels were randomly sampled from the 2004 Beijing Medical Insurance Database ,and analyzed in terms of indication, dosage, treatment course and ADR.RESULTS： A total of 676 cases were sampled with more than 25 kinds of indications,and among the top 10 indications, 18.0% were inconsistent with the instructlon,and 17.5% were in lack of evidence support such as randomized controlled trials. Individual dose of Xingnaojing Injection was（27.9 ± 9.0）mL, which was higher than the usual dose described by the instructions and clinical trials.The mean treatment course of Xingnaojing Injeciton was 14.6 days,with 20.9% exceeding 20 days.Drugs used in combination with Xingnaojing Injection included anti-thrombosis agents（13.3% ） and traditional Chinese medicines with the action of promoting blood circulation and removing blood stasis （12.7%） . CONCLUSION： The use of Xingnaojing injection in medical insurance patients was not consistant with the instruction or evidence supported by clinical trials.

关 键 词：醒脑静注射液 医疗保险 药品说明书 循证医学 合理用药 

分 类 号：R286[医药卫生—中药学]