番茄红素和维生素E复合剂的抗氧化作用实验研究  

Experimental Study on Antioxidation Effect of Lycopene and Vitamin E Compounding Agent

作　　者：张聪恪[1] 李金环[2] 

机构地区：[1]河南省疾病预防控制中心,河南郑州450003 [2]河南省中医院

出　　处：《实用预防医学》2007年第1期60-61,共2页Practical Preventive Medicine

摘　　要：目的研究番茄红素和维生素E复合剂对实验性老龄大鼠抗氧化的影响。方法将40只12月龄SD雄性大鼠按照血清中丙二醛(MDA)的含量随机分为低、中、高剂量组和一个老龄对照组,连续灌胃60d后采血并分离血清,测定MDA含量、超氧化物歧化酶(SOD)和谷胱甘肽过氧化物酶(GSH-Px)的活力。结果该复合剂具有增强SOD和GSH-Px活性和降低MDA的作用。结论番茄红素和维生素E复合剂具备抗氧化功能。Objective To study the antioxidation effect of lycopene and vitamin E compounding agent in experimental old rats. Methods Forty male SD rats aged 12- month were randomly divided into four groups by MDA contents, which were low dose, middle doseand high dose treatment groups and a control group, after continously intragastric infusion for 60 days, serum MDA, SOD and GSH- Px were determined. Result The lycopene and vitamin E compounding agent boosted up the SOD and GSH- Px activity, reduced the MDA content. Conclusion The lycopene and vitamin E compounding：agent has antioxidation effects.

关 键 词：番茄红素 维生素E 抗氧化作用 

分 类 号：R155.5[医药卫生—营养与食品卫生学]