黄连副产物体外抗氧化活性研究  

In Vitro Antioxidant Activity of Water Extracts from Different Parts of Coptis Plants

作　　者：屠大伟[1] 张保顺[2] 李学刚[2] 

机构地区：[1]西南大学食品学院,重庆400715 [2]西南大学药学院药用资源化学研究所,重庆400715

出　　处：《中国农学通报》2007年第4期108-111,共4页Chinese Agricultural Science Bulletin

摘　　要：研究了黄连副产物-须根、茎叶及花薹水提物的抗氧化能力。结果表明:黄连须根、茎叶及花薹均表现出了直接清除羟自由基(·OH)、超氧自由基(O2-·)、过氧化氢(H2O2)活性及抗猪油自动氧化的活性。须根、茎叶和花清除羟自由基(·OH)的IC50依次为11.85、7.21和11.22mg/ml;清除超氧自由基(O2-·)的IC50依次为2.42、1.77和2.76mg/ml;清除过氧化氢(H2O2)的IC50依次为0.8、0.76、1.07mg/ml。同时黄连三种副产物的水提物还表现出一定的抗猪自动氧化的活性。Antioxidant Activity of Water Extracts from fiber root, leaf and flower of Coptis plant was studied. The result indicated that the water extracts from all parts of this plant exerted a relative strong antioxidant activity. The IC50 for hydroxyl free radical scavenging of the extracts from fibre, leaf and flower were 11.85, 7.21 and 11.22 mg/ml, respectively. Consequently, IC50 for hydrogen peroxide scavenging of the extracts were 0.8,0.76,and 1.07mg/ml, respectively. The fibre, leaf and flower with IC50 2.42, 1.77 and 2.76mg/ml, respectively, also showed strong ability to eliminate O2-· Antioxidant Activities of the extracts increased when the extract concentration increased.

关 键 词：黄连副产物 抗氧化 自由基 

分 类 号：TS202.3[轻工技术与工程—食品科学]