多溴二苯醚动物毒理学研究进展及其生态毒理学展望  

Research advances in animal toxicology of polybrominated diphenyl ethers and expectations on their ecotoxicology.

作　　者：徐志强[1] 周启星[1] 张悫[2] 祝凌燕[3] 

机构地区：[1]中国科学院沈阳应用生态研究所陆地生态过程重点实验室 [2]沈阳广播电视大学高职学院,沈阳110003 [3]南开大学环境科学与工程学院,天津300071

出　　处：《应用生态学报》2007年第5期1143-1152,共10页Chinese Journal of Applied Ecology

基　　金：国家重点基础研究发展规划项目(2004CB418503);国家杰出青年科学基金资助项目(20225722)

摘　　要：多溴二苯醚(PBDEs)作为阻燃剂,已被广泛应用于工业产品和家庭用品中.近年来,在土壤、沉积物、大气和生物体中普遍检测出PBDEs.PBDEs对哺乳动物、鸟类和鱼类都存在不同程度的毒害作用,其分布的广泛性、难降解性和对人体健康的不确定性已引起人们的普遍关注.基于国外动物毒理学研究成果,综合论述了PBDEs在生物体内的累积和排泄及其对动物肝酶活性、甲状腺、生殖和发育、神经系统和免疫系统等的影响及其潜在的人体健康危害,并分析了目前PBDEs毒理学研究中的问题,展望了未来PBDEs生态毒理学的研究方向.As a kind of flame retardants, polybrominated diphenyl ethers （PBDEs） have been widely applied in industrial products and house wears, and detected in soil, sediments, air, and living organisms. PBDEs are proved to be harmful to mammals, birds, and fish. Great concern has been aroused because of their wide spreading, stable structure, and uncertain risk to human health. Based on the foreign toxicological researches and findings, this paper summarized the accumulation and elimination of PBDEs in organisms, their effects on the hepatic enzyme activities, thyroid gland, nerve and immune system, and reproduction and development of animals, and potential risk to human health. The problems in PBDEs toxicological research were analyzed, and future directions in this field were discussed.

关 键 词：多溴二苯醚 生态毒理学 人体健康风险 

分 类 号：X171.5[环境科学与工程—环境科学]