牦牛骨粉对大鼠骨钙、骨密度及骨钙吸收率影响的研究  

Effects of Yak Bone Powder on Rat Bone Calcium,Bone Density and Calcium Apparent Absorption Rate

作　　者：赵要武[1] 许继取[1] 朱清华[1] 杨雪锋[1] 

机构地区：[1]华中科技大学同济医学院公共卫生学院营养与食品卫生学系,湖北武汉430030

出　　处：《食品科学》2007年第6期321-323,共3页Food Science

摘　　要：目的:研究牦牛骨粉钙吸收率及对大鼠骨钙、骨密度的影响。方法:清洁级雌性SD大鼠,70只,随机分为7组,即低钙对照组(饲料中含钙量为1180mg/kg),牦牛骨粉高、中、低三个剂量组(相当于人体推荐摄入量的5、10、20倍),实测值饲料中含钙量为1437、1852、2778mg/kg,另设与样品对照组剂量相对应的三个碳酸钙对照组。于实验第4w末进行三天的钙代谢试验。整个喂养时间为12w,实验结束日,测右侧股骨长度,干重,骨钙含量及骨密度。结果:牦牛骨粉10、20倍剂量组股骨钙含量、股骨骨密度高于低钙对照组,5、20倍剂量组钙表观吸收率高于相应剂量的碳酸钙对照组(p<0.05)。结论:牦牛骨粉不仅有增加骨密度功能,并具有较高的钙表观吸收率。Objective： To investigate the effects of yak bone powder on the bone density, bone calcium content and bone calcium apparent absorption rate in rats. Method： Seventy female SD rats were divided into 7 groups. The low calcium control group was fed with 1180 mg Ca/kg in diet. The three experiment groups were fed three dosage of yak bone powder, corresponding to 5, 10, 20, times of the recommended dosage for human body. Ca contents in the three groups are respectively 1437, 1852, 2778 mg/kg of diet. For another three groups, Ca contents in the diet were the same as the experiment groups, but using calcium carbonate as control. At the end of the fourth week, calcium metabolic experiment was performed for 3 days. Food intake was recorded and feces were collected for calcium contents assay. Calcium apparent absorption rate was also assayed. Twelve weeks later, bone calcium, bone density, bone length and femur bone weight were all assayed. Result： The results showed that yak bone powder shows higher calcium apparent absorption rate than calcium carbonate. Bones Ca content and bone density in yak bone powder groups are significant and higher than those in the low Ca control group. However, there are no significant differences between yak bone powder group and calcium carbonate group. Conclusion： Yak bone powder may improve bone density and have a higher apparent absorption rate than calcium carbonate.

关 键 词：牦牛骨粉 骨钙 骨密度 钙表观吸收率 大鼠试验 

分 类 号：TS251.94[轻工技术与工程—农产品加工及贮藏工程]