噻二嗪硫酮衍生物的合成及抑菌活性研究  

Synthsis and antimicrobial activities of some new tetrahydro-2H-1, 3, 5 - thione derivatives

作　　者：宋全道[1] 米广太[1] 李忠[1] 丁易[2] 

机构地区：[1]山东医科大学药学系,济南250012 [2]济南市科技信息研究所

出　　处：《天津药学》1997年第1期15-17,共3页Tianjin Pharmacy

摘　　要：合成了4种新的3-苯基-5-取代的-四氢-2H－1，3,5-噻二嗪-2-硫酮类化合物，其结构被红外光谱与紫外光谱及元素分析所证实，并进行了初步抑菌活性试验。A number of new 3 - phenyl - 5 - substituted - tetrahydro - 2H - 1, 3, 5 - thiadiazine - 2 - thiones have been synthesized as antibacterial and antifungal compounds. The structure of these compounds have been elucidated by UV, IR and elmentary analysis. The antibacterial and antifungal activities were tested in vitro. The research data showed these compounds have certain biological activity.

关 键 词：合成 抑菌活性 噻二嗪硫酮 衍生物 

分 类 号：R965.2[医药卫生—药理学] TQ463.54[医药卫生—药学]