原发性生殖器恶性黑色素瘤15例临床分析  

Clinical Analysis of 15 Patients with Primary Malignant Melanoma in the Genital Tract

作　　者：王亚军[1] 常文庆[1] 卜大伟[1] 

机构地区：[1]中国医科大学第一临床学院妇科

出　　处：《中华妇产科杂志》1997年第4期226-228,共3页Chinese Journal of Obstetrics and Gynecology

摘　　要：目的：探讨原发性生殖器恶性黑色素瘤的诊断、治疗特点及影响预后的因素。方法：对我院收治的１５例原发性生殖器恶性黑色素瘤的临床资料进行回顾性分析。结果：发生于外阴、阴道，宫颈的黑色素瘤分别为４例、９例、２例。１１例行手术切除辅以化疗加免疫疗法，４例行化疗和免疫等疗法。１５例中，１例失访，５例生存＜１年，７例＜２年，２例＞３年，其中１例存活１９年。结论：原发性生殖器恶性黑色素瘤预后差。其治疗以手术为主，并辅以化疗和免疫疗法的综合治疗。Objective: To analyse the clinical characteristics and prognosis of primary malignant melanoma in female genital tract. Methods: Clinical data of 15 patients with primary malignant genital melanoma were analysed retrospectively. The tumors occurred in the vulva (4 patients), in vagina (9) and in uterine cervix (2). 11 of them were treated by surgery combined with chemotherapy and immunotherapy, the remaining 4 by chemotherapy and immunotherapy only. Results: All cases except one were followed up. The survival periods were shorter than 1 year in 5 patients, shorter than 2 years in 7. Two were alive for more than 3 years and 1 for more than 19 years. Conclusions: The prognosis of primary maglinant melanoma is rather poor. Surgery combined of chemotherapy and immunotherapy is the main therapeutic approach.

关 键 词：黑色素瘤 女生殖器肿瘤 综合疗法 

分 类 号：R737.305[医药卫生—肿瘤]