帕罗西汀合并认知行为疗法治疗伴焦虑症状抑郁症的对照研究  

Paroxitine plus cognitive behavior therapy in treatment of depression associated with anxiety

作　　者：陈红生[1] 崔中兰[1] 王泉英[1] 

机构地区：[1]滨州市人民医院精神卫生中心,滨州市256610

出　　处：《滨州医学院学报》2007年第4期274-275,共2页Journal of Binzhou Medical University

摘　　要：目的评价帕罗西汀合并认知行为疗法对伴焦虑症状抑郁症的治疗效果。方法符合CCDM-3抑郁症的诊断标准,并且汉密尔顿焦虑量表(HAMA)评分>14分的门诊及住院患者58例,随机分为两组:治疗组给予帕罗西汀合并认知行为治疗,对照组只给予帕罗西汀治疗,为期6周,于治疗前及治疗后第1、2、4、6周末用汉密尔顿抑郁量表(HAMD)、汉密尔顿焦虑量表(HAMA)评定疗效。结果在治疗第1、2、4、6周末治疗组疗效优于对照组,尤其对焦虑症状疗效更好,具有极显著性差异(P<0.01)。结论帕罗西汀合并认知行为疗法治疗伴焦虑症状的抑郁症效果优于单用帕罗西汀。Objective To compare the effect of paroxitine plus cognitive behavior in treatment of depression associated with anxiety. Methods Measuring up the diagnosis of CCMD-3, and using HAMA to mark 58 cases of clinic and in-patient which is over 14, dividing into two groups at random. The rapeutic group was given parositine in addition to cognitive behavior therapy, and control group was given paroxitine alone,having a 6-week therapy,and taking use of HAMD and HAMA to evaluate the curing effect before treating and 1,2,4,6 week after treating. Results The therapeutic efficacy in paroxitine plus cognitive behavior therapy group was significantly better than that in control group. Conclusion Paroxitine plus cognitive behavior therapy has better effect in treatment of depression associated with anxiety.

关 键 词：帕罗西汀 认知行为疗法 伴焦虑症状的抑郁症 

分 类 号：R749[医药卫生—神经病学与精神病学]