桑叶不同组分降血糖作用研究  

Study on Hypoglycemic Effects of Components in Mulberry Leaves

作　　者：杨雨[1] 欧阳臻[1] 常钰[1] 孟夏[1] 

机构地区：[1]江苏大学药学院,江苏镇江212013

出　　处：《食品科学》2007年第8期454-456,共3页Food Science

基　　金：江苏省农业科技攻关项目(BE2004352)

摘　　要：目的:研究桑叶不同组分的降血糖作用,筛选桑叶中降血糖作用活性组分。方法:采用四氧嘧啶诱导的糖尿病小鼠模型,观察桑叶不同组分对四氧嘧啶诱导的糖尿病小鼠血糖及肝糖原的影响。结果:桑叶多糖组分和桑叶生物碱组分能有效降低糖尿病小鼠的血糖,促进肝糖合成,增加肝糖原。桑叶黄酮组分无明显的降血糖和增加肝糖原作用。结论:桑叶多糖组分和桑叶生物碱组分有较好的降血糖作用,能有效降低四氧嘧啶糖尿病小鼠的血糖,促进肝糖合成,增加肝糖原。Objective： To study the hypoglycemic effect of components in mulberry leaves and screen the active hypoglycemic components. Method： Use alloxan-induced diabetic mice as experimental animal, and observe the hypoglycemic effect of components in mulberry leaves. Result： It is found that the polysaccharide and the alkaloid in mulberry leaves can decrease blood glucose, promote synthesis of liver starch and increase hepatic glycogen of the diabetes mice efficiently. But the flavonoid in mulberry leaves has no significant hypoglycemic effect. Conclusion： The polysaccharide and the alkaloid in mulberry leaves have hypoglycemic effect. They can decrease blood glucose, promote synthesis of liver starch and increase hepatic glycogen of the diabetes mice induced by alloxan efficiently.

关 键 词：桑叶组分 糖尿病模型 降血糖作用 血糖 肝糖原 

分 类 号：R282[医药卫生—中药学]