广东省人群中人嗜T细胞病毒Ⅰ型感染的血清流行病学调查及其与人类疾病的关系  

A seroepidemiological survey: Antibody to HTLV-1 in sera from various populations in Guangdong Province

作　　者：杨棉华[1,2,3] 陈国敏[1,2,3] 余秀葵[1,2,3] 庄春兰[1,2,3] 郑璇 庄坚[1,2,3] 陈慎奔 廖传红[1,2,3] 张永利[1,2,3] 曾毅 

机构地区：[1]广东省汕头大学医学院 [2]中国预防医学科学院病毒学研究所 [3]汕头大学医学院第一附属医院

出　　处：《中华实验和临床病毒学杂志》1997年第1期56-58,共3页Chinese Journal of Experimental and Clinical Virology

摘　　要：收集广东省各类人群血清标本２２２４份，用间接免疫荧光法检测人类嗜Ｔ细胞病毒Ⅰ型（ＨＴＬＶ－１）抗体，结果：ＨＴＬＶ－１抗体阳性３５份，总阳性率为１．５７％；其中健康人群血清１８１０份，抗体阳性２３份，阳性率为１２７％；献血员血清２４８份，抗体阳性１份，阳性率０４０％；白血病患者血清１０９份，阳性８份，阳性率７３４％，与健康人群比较，有非常显著性差异（Ｐ＜０００５）；神经系统疾病患者血清５７份，阳性３份，阳性率５２６％。A seroepidemiological survey of HTLV-1 infection in Guangdong Province was reported. 2224 serum samples from various populations were collected and antibodies to HTLV-1 in sera were detected with indirect immunofluorescent assay. Total seropositive rate was 1.57% (35/2224). The antibody positive rates of HTLV-1 in sera from healthy individuals (n=1810)、blood donors (n=248)、patients with T cell leukemia (n=109) and patients with neurological diseases (n=57) were 1.27%, 0.40%, 7.30% and 5.26% respectively. There was a significant difference between the patients with T cell leukemia and the healthy individuals (P<0.005).

关 键 词：白血病 抗体 病因学 病毒学 HTLV-1 

分 类 号：R733.702[医药卫生—肿瘤]