微波辐射-同步冷却法合成3种2-甲基-2-烷基-1，3-二噻烷  

Synthesis of Three 2-Alkyl-2-Methyl-1,3-Dithianes Using Microwave Irradiation-Simultaneous Cooling Method

作　　者：郑福平[1] 张文静[1] 孙宝国[1] 谢建春[1] 刘玉平[1] 徐晓东[1] 李宁[1] 

机构地区：[1]北京工商大学化学与环境工程学院,北京100037

出　　处：《现代科学仪器》2007年第4期81-84,共4页Modern Scientific Instruments

基　　金：国家自然科学基金项目(20376003)

摘　　要：本文描述了一种合成2-甲基-2-烷基-1，3-二噻烷香料化合物的便捷方法。采用微波辐射-同步冷却技术，1，3-丙二硫醇分别与丁酮、戊酮和己酮在一水合对甲基苯磺酸催化下以微波功率63W反应15min，合成了2-甲基-2-乙基-1，3-二噻烷、2-甲基-2-丙基-1，3-二噻烷和2-甲基-2-丁基-1，3-二噻烷，产率分别为74．8％、72．4％和76．8％。采用元素分析、FTIR、^1H NMR和GC-MS对3种产物进行了结构鉴定，并进行了初步香气评价。In this study, we describe a convenient method to synthesize 2-alkyl-2-methyl-1,3-dithianes flavoting compounds. 2-Ethyl-2-methyl-1,3-dithiane, 2-methyl-2-propyl-1,3 -dithiane and 2-butyl-2-methyl-1,3-dithiane were synthesized by the reaction of 1,3-dithiolpropane with 2-butanone, 2-pentanone and 2-hexanone in turn, catalyzed by p-toluenesulfonic acid monohydrate with the reaction times of 15min and the microwave power of 63W. A microwave irradiation - simultaneous cooling method was used. Yields of above three products were 74. 8%, 72.4% and 76.8% respectively. Structures of above three products were identified by data of elemental analysis, FTIR, ^1H NMR and GC -MS. The aroma characteristics were evaluated fundamentally.

关 键 词：微波辐射-同步冷却法 2-甲基-2-烷基-1 3-二噻烷 合成 香料 

分 类 号：TQ252[化学工程—有机化工]