我国南方青少年肠易激综合征流行病学调查  

An epidemiological study of irritable bowel syndrome in adolescents in southern China

作　　者：姚敏[1] 陈燕萍[1] 周惠清[2] 宋艳艳[3] 李定国[2] 

机构地区：[1]上海中医药大学附属岳阳中西医结合医院儿内科,上海200437 [2]上海交通大学医学院附属新华医院消化内科,上海200092 [3]上海交通大学医学院统计教研室,上海200025

出　　处：《临床儿科杂志》2007年第10期835-839,共5页Journal of Clinical Pediatrics

基　　金：上海市教育发展基金会课题(No.2005001)

摘　　要：目的分析我国南方城市中小学生肠易激综合征(IBS)的患病率及分布特征。方法采用多级整群随机抽样方法,对我国南方16727名城市中小学生进行流行病学问卷调查。结果符合Manning及罗马Ⅱ诊断标准的IBS期间患病率分别为53.29%及19.58%,以高中生居多,男女患病率差异无统计学意义(P>0.05);在符合罗马Ⅱ标准的IBS患者中,17.92%(587例)为腹泻型;48.93%(1602例)为便秘型;33.15%(1086例)为腹泻便秘交替型;③在符合Manning标准及罗马Ⅱ标准的IBS学生中,因腹痛或不适及大便习惯改变而就诊者分别为11.33%及16.85%。结论IBS是城市中小学生的常见病及多发病,患病率随年龄的增长而上升。Objectives To investigate the prevalence and distribution characteristics of irritable bowel syndrome （IBS） in adolescents in the southern cities of China. Methods This study included 16 727 students from primary and middle schools in southern China. All students studied were requested to fill in a questionnaire. The stratified, random and cluster sampling methods were used. Results （1） The adjusted prevalence of IBS was 53.29% according to the Manning criteria while 19.58% according to the Rome 11 criteria. The highest prevalence of IBS was found in high school students but with no significance gender difference （P 〉 0.05）. （2） Among all the students fulfilling Rome 11 criteria, 17.92% （n = 587） were diagnosed as diarrhea predominant IBS, 48.93% （n = 1 602） were constipation predominant IBS, and 33.15% （n = 1 086） were alternating IBS. （3） The rate of health-seeking in the IBS students was 11.33% according to Manning criteria while 16.85% according to Rome 11 criteria. Conclusions Irritable bowel syndrome is a common disorder among the adolescents and its prevalence increases with age.

关 键 词：肠易激综合征 青少年 流行病学 

分 类 号：R574.4[医药卫生—消化系统]