Synthesis, Characterization and Activity against Staphylococcus of Metal（Ⅱ）-Gatifloxacin Complexes  

作　　者：李泽全 吴锋景 龚云 胡长文 张云怀 甘孟瑜 

机构地区：[1]Department of Chemistry, College of Chemistry and Chemical Engineering, Chongqing University, Chongqing 400044, China [2]Department of Chemistry, Beijing Institute of Technology, Beijing 100081, China

出　　处：《Chinese Journal of Chemistry》2007年第12期1809-1814,共6页中国化学（英文版）

基　　金：Project supported by the Natural Science Young Scholars Foundation of Chongqing University, the National Natural Science Foundation of China （No. 20331010） and Chongqing University Postgraduates＇ Science and Innovation Fund.

摘　　要：Three novel isostructural complexes M（gatx）2（H2O）2·4H2O [gatx=gatifloxacin, M = Zn （1）, Ni （2） and Co （3）] were synthesized at room temperature and structurally characterized by elemental analysis, IR and single crystal X-ray diffraction, which exhibit a similar mononuclear structure, in which the metal ion is coordinated by two gatifloxacin and two aqua ligands to furnish a distorted octahedral geometry, and show different activities against staphylococcus due to the different metal ions in the structures.Three novel isostructural complexes M（gatx）2（H2O）2·4H2O [gatx=gatifloxacin, M = Zn （1）, Ni （2） and Co （3）] were synthesized at room temperature and structurally characterized by elemental analysis, IR and single crystal X-ray diffraction, which exhibit a similar mononuclear structure, in which the metal ion is coordinated by two gatifloxacin and two aqua ligands to furnish a distorted octahedral geometry, and show different activities against staphylococcus due to the different metal ions in the structures.

关 键 词：SYNTHESIS structure GATIFLOXACIN metal ion ACTIVITY 

分 类 号：O6[理学—化学]