类风湿性关节炎啮齿动物模型的研究进展  

Recent Advances in Research on Rodent Models of Rheumatoid Arthritis

作　　者：刘元刚[1] 刘树滔[1] 饶平凡[1] 

机构地区：[1]福州大学生物工程研究所,福州350002

出　　处：《中国实验动物学报》2007年第6期470-473,共4页Acta Laboratorium Animalis Scientia Sinica

摘　　要：类风湿性关节炎是一种常见的致残性疾病之一,病因未明。研究此类疾病的有效方法是建立、研究并应用动物模型。通过对目前国内外类风湿性关节炎模型复制方法、机制和应用的研究,分析各自的特点及不足之处,提出复制更加符合类风湿性关节炎临床特点的动物模型的展望与设想。Rheumatoid arthritis （RA） is a common disease that causes deformities, but its pathology is not fully clear. Establishment and application of the animal models is an effective method for RA research. In this article the methodology, mechanisms and applications of current animal models of RA were reviewed, their characteristics and drawbacks were analyzed, and prospective directions of rodent animal models of RA were put forward.

关 键 词：类风湿性关节炎 模型 啮齿动物 综述 

分 类 号：R-332[医药卫生]