微波催化一锅法快速合成10-羟基癸酸的研究  

Study on microwave catalyzed synthesis of 10-hydroxy decanonic acid by one-pot method

作　　者：黎彧[1] 李善吉[2] 林春晓[3] 黄利[4] 

机构地区：[1]广东轻工职业技术学院轻化系,广东广州510300 [2]广东省嘉应学院,广东梅州514015 [3]深圳市南山区妇幼保健院,深圳518052 [4]广东药学院药科学院,广东广州510006

出　　处：《中国酿造》2008年第1期47-48,共2页China Brewing

基　　金：广东省自然科学基金资助(06023571);广东轻院科研启动基金资助(200503);广东轻院教育改革和实践工程资助

摘　　要：研究了用微波催化快速合成10-羟基癸酸的新工艺,以蓖麻油60mL、氢氧化钠75 g和2-辛醇120mL为原料,微波功率为250W,经微波催化快速合成可使10-羟基癸酸的产率达到69%。该法与传统合成工艺相比,微波催化反应可在常温常压下进行,中间产物不需分离,反应时间由6h减小为16min,加快了反应速度。A new one-pot method with microwave-catalyzed synthesis was applied to produce 10-hydroxy decanonic acid from the caster oil. The processes were investigated and the reaction conditions were confirmed as follows： the reagents included 60 ml caster oil, 75 g NaOH and 120 ml 2-octyl alcohol; the microwave power was 250 W. Finally the yield was 69 %. Compared with the traditional synthesis method, this method reduced reaction time from 6 h to 16 min.

关 键 词：10-羟基癸酸 微波合成 蓖麻油 一锅法 

分 类 号：TS202.3[轻工技术与工程—食品科学]