双歧啤酒对小鼠免疫功能的影响  

Effect of Brewing Bifidobeer on Immunological Function of Mice

作　　者：穆小萍[1] 张德纯[1] 邱建[1] 蒲荣[1] 

机构地区：[1]重庆医科大学临床检验诊断学省部共建教育部重点实验室,重庆医科大学病原生物学教研室,重庆400016

出　　处：《食品科学》2008年第1期306-308,共3页Food Science

基　　金：重庆医科大学科技创新基金项目(200533)

摘　　要：目的:研究双歧啤酒对小鼠免疫功能的影响。方法:将小鼠随机分成纯净水对照组、市售啤酒对照组和双歧啤酒低、中、高三个剂量组,剂量分别为25、50、100ml/kgbw,饮水法喂饲小鼠,测定小鼠胸腺和脾脏重量、腹腔巨噬细胞吞噬功能、血清溶血素抗体水平、皮肤迟发型超敏反应(DTH)程度。结果:与对照组比较,双歧啤酒高、中剂量组能显著增强巨噬细胞吞噬功能,增加血清溶血素抗体水平和DTH程度。结论:双歧啤酒能提高机体的免疫功能。Objective： To explore the effect of brewing bifidobeer on immuniological function of mice. Methods： Mice were randomly assigned to 5 groups： the purified water control group, the ordinary beer control group and three brewing bifidobeer groups（drunk the purified water containing brewing bifidobeer 25,50,100 ml/kg bw）. The weight of thymus and spleen, the phagocytic capability of celiac macrophage, the level of serolysin and the degree of cutaneous delayed type hypersensitivity of mice were evaluated. Result The phagocytic capability of celiac macrophage, the level of serolysin and the degree of cutaneous delayed type hypersensitivity of high dose and medium dosage brewing bifidobeer groups increased significantly compared with control groups. Conclusion： Brewing bifidobeer can enhance the immuniological function of mice.

关 键 词：双歧啤酒 免疫功能 小鼠 

分 类 号：TS262.5[轻工技术与工程—发酵工程]