葡萄糖酸钙对肌苷发酵中糖代谢途径关键酶酶活力的影响  

Effect of Calcium Gluconate on Activities of Key Enzymes in Glucose Metabolic Pathway during Inosine Fermentation

作　　者：郭元昕[1] 陈双喜[2] 郝玉有[1] 储炬[1] 庄英萍[1] 

机构地区：[1]华东理工大学生物反应器工程国家重点实验室,上海200237 [2]河南大学生命科学学院,河南开封475001

出　　处：《中国医药工业杂志》2008年第4期254-257,共4页Chinese Journal of Pharmaceuticals

基　　金：上海市曙光计划资助项目(01SG28);上海市科委重点科技攻关项目(034319220)

摘　　要：在肌苷发酵过程中向培养基中添加葡萄糖酸钙,研究其对葡萄糖代谢途径中关键酶酶活力和肌苷合成的影响,结果显示适量的葡萄糖酸钙能提高6-磷酸葡萄糖脱氢酶和葡萄糖激酶的酶活力,促进肌苷的合成。Calcium gluconate was added into the culture medium in the process of inosine fermentation. Its effect on key enzyme activities of glucose metabolism and inosine synthesis was studied. The result showed that calcium gluconate could enhance the activities of both glucose-6-phosphate dehydrogenase and glucokinase, and stimulate the inosine biosynthesis.

关 键 词：肌苷 发酵 葡萄糖酸钙 葡萄糖代谢 酶活力 

分 类 号：TQ920.6[轻工技术与工程—发酵工程]