物化条件对多肽聚集的影响  

Effect of Physicochemical Conditions on the Aggregation of Peptides

作　　者：于泓鹏[1] 吴克刚[1] 柴向华[1] 

机构地区：[1]广东工业大学食品科学与生物工程系

出　　处：《食品与发酵工业》2008年第3期40-43,共4页Food and Fermentation Industries

基　　金：广东工业大学博士启动基金(063034)

摘　　要：研究了物化条件对水解多肽聚集的影响。高温有利于多肽的聚集,而低温有利于最终聚集物结构的稳定,说明疏水相互作用不是导致水解多肽聚集的唯一作用力;低离子强度条件下pH4.0时有利于聚集物的稳定存在;聚集物随着溶液介电常数的降低而解聚,而冷冻干燥后聚集物呈相反变化趋势。The paper reported the effect of physicochemical conditions on the aggregation of peptides. Higher temperature significantly favored the aggregation, but less number of aggregates were formed at the higher temperature, indicating that the aggregation reaction was not simply the contribution of hydrophobic interactions. The stability of these aggregates was also measured as a function of pH, in the presence of dif- ferent concentrations of salt or alcohol. Maximum stability occurred at pH 4.0. The stability of aggregate decreased with decreasing dielectric constant, while the aggregate of freeze drying showed a reverse trend.

关 键 词：物化条件 多肽 聚集 

分 类 号：TS201.2[轻工技术与工程—食品科学]