An insulinoma with clinical and electroencephalographic features resembling complex partial seizures  

作　　者：Shuang WANG Hai-tao HU Shu-qun WEN Zhong-jin WANG Bao-rong ZHANG Mei-ping DING 

机构地区：[1]Department of Neurology, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China

出　　处：《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2008年第6期496-499,共4页浙江大学学报（英文版）B辑（生物医学与生物技术）

基　　金：Project(No.30600194)supported by the National Natural Science Foundation of China

摘　　要：We described a female patient with insulinoma who experienced recurrent episodes of automatism, confusion and convulsion. Furthermore, her electroencephalography （EEG） findings resembled the pattern in complex partial seizures with secondary generalization. The interictal EEG showed spikes and sharp waves, as well as focal slowing over the left temporal lobe, and the ictal EEG revealed generalized spikes and sharp waves associated with diffused slowing. She was initially misdiagnosed as pharmacoresistant epilepsy. After the insulinoma was found and surgically removed, her EEG turned normal and she was seizure-free during the 4-year follow-up. This report highlights the need for careful reassessment of all seizures refractory to medication, even for the oatients associated with eoileotiform discharges on EEG.We described a female patient with insulinoma who experienced recurrent episodes of automatism,confusion and convulsion.Furthermore,her electroencephalography(EEG)findings resembled the pattern in complex partial seizures with secondary generalization.The interictal EEG showed spikes and sharp waves,as well as focal slowing over the left temporal lobe,and the ictal EEG revealed generalized spikes and sharp waves associated with diffused slowing.She was initially misdiagnosed as pharmacoresistant epilepsy.After the insulinoma was found and surgically removed,her EEG turned normal and she was sei- zure-free during the 4-year follow-up.This report highlights the need for careful reassessment of all seizures refractory to medi- cation,even for the patients associated with epileptiform discharges on EEG.

关 键 词：INSULINOMA HYPOGLYCEMIA Electroencephalography （EEG） SEIZURE 

分 类 号：R736.7[医药卫生—肿瘤]