Adrenal myelolipoma within myxoid cortical adenoma associated with Conn's syndrome  

作　　者：Hong-sheng LU Mei-fu GAN Han-song CHEN Shan-qiang HUANG 

机构地区：[1]Department of Pathology, Taizhou Hospital, Linhai 317000, China

出　　处：《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2008年第6期500-505,共6页浙江大学学报（英文版）B辑（生物医学与生物技术）

摘　　要：The coexistence of myelolipoma within adrenal cortical adenoma is extremely rare,for both tumors present usually as separate entities.There are only 16 such cases reported worldwide.To the best of our knowledge,the case we reported here is the first one of myxoid adrenal cortical adenoma associated with myelolipoma reported.A 32-year-old Chinese woman with 4-year history of hypertension was presented in our study.Computed tomography(CT)of the abdomen showed a large heterogene- ously-enhancing mass(4.5 cm in diameter)in the left suprarenal region.Clinical history and laboratory results suggest a metabolic disorder as Conn's syndrome.The patient underwent a left adrenalectomy,and a histopathological study confirmed the mass to be a myxoid adrenal cortical adenoma containing myelolipoma.The patient was postoperatively well and discharged uneventfully.In the present case report,we also discuss the etiology of simultaneous myelolipoma and adrenal adenoma associated with Conn's syndrome,and the methods of the diagnosis and differential diagnosis.The coexistence of myelolipoma within adrenal cortical adenoma is extremely rare, for both tumors present usually as separate entities. There are only 16 such cases reported worldwide. To the best of our knowledge, the case we reported here is the first one of myxoid adrenal cortical adenoma associated with myelolipoma reported. A 32-year-old Chinese woman with 4-year history of hypertension was presented in our study. Computed tomography （CT） of the abdomen showed a large heterogeneously-enhancing mass （4.5 cm in diameter） in the left suprarenal region. Clinical history and laboratory results suggest a metabolic disorder as Conn＇s syndrome. The patient underwent a left adrenalectomy, and a histopathological study confirmed the mass to be a myxoid adrenal cortical adenoma containing myelolipoma. The patient was postoperatively well and discharged uneventfully. In the present case report, we also discuss the etiology of simultaneous myelolipoma and adrenal adenoma associated with Conn＇s syndrome, and the methods of the diagnosis and differential diagnosis.

关 键 词：Adrenal gland Myxoid adrenal cortical adenoma MYELOLIPOMA Conn＇s syndrome PATHOLOGY IMMUNOHISTOCHEMISTRY 

分 类 号：R73[医药卫生—肿瘤]