蛋白质β-发夹模体片断的识别  

RECOGNITION OF β-HAIRPIN MOTIFS IN PROTEINS

作　　者：姜雪[1] 胡秀珍[1] 

机构地区：[1]内蒙古工业大学理学院

出　　处：《内蒙古工业大学学报（自然科学版）》2008年第2期88-94,共7页Journal of Inner Mongolia University of Technology：Natural Science Edition

基　　金：内蒙古自然科学基金资助项目200508010509

摘　　要：依据β-发夹氨基酸序列中的保守性特征,分别以氨基酸(20种氨基酸和一个空位)和氨基酸紧邻关联为参数,通过构建位置权重矩阵和选取氨基酸最佳序列模式片断,利用相似性打分函数,对蛋白质超二级结构β-发夹模体片断进行识别,获得了较好的预测效果.Based on the conservative performance of amino acid sequence,prediction of β-hairpin motifs in supersecondary protein structure is made. Amino acid composition and dipeptide composition are taken as parameters. Position weight matrix is constructed and optimal sequence pattern segment is selected. Then, by use of similarity scoring function,β-hairpin motifs of supersecondary protein structure are recognized. The prediction results turn out to be quite satisfactory.

关 键 词：Β-发夹模体 位置权重矩阵 相似性打分函数 域值 

分 类 号：Q61[生物学—生物物理学]