多孔玉米淀粉吸附氨茶碱药物的研究  

Adsorption of Porous Corn Starch for Aminophylline

作　　者：应雪肖[1] 钱俊青[1] 吕彬峰[1] 吴沈洁[1] 王玉妃[1] 

机构地区：[1]浙江工业大学药学院,杭州310014

出　　处：《中国粮油学报》2008年第3期47-50,共4页Journal of the Chinese Cereals and Oils Association

摘　　要：用真菌淀粉酶酶解制成多孔玉米淀粉,研究探讨了以其作为药物载体吸附氨茶碱的性能,并建立了一种特殊的紫外分光光度测定多孔淀粉吸附氨茶碱量的方法。多孔淀粉吸附氨茶碱的最佳条件是氨茶碱初始浓度40mg/mL,温度20℃,时间为60 min,pH 9.5,在此条件下,吸附量达到79.26 mg/g,比原淀粉的吸附能力提高了3.1倍。Porous corn starch was prepared by using fungal amylase; the adsorption performance of the porous com starch for aminophylline as medicament carrier were investigated; and a special ultraviolet spectmphotometry method to determine the quantity of the adsorbed aminophylline was established. The optimal adsorption conditions determined are initial concentration of aminophylline 40 mg/mL, temperature 20 ℃, time 60 min, and pH 9.5. The actual adsorption amount under the optimum conditions is up to 79.26 mg/g, 3.1 times more than that of the original starch.

关 键 词：真菌淀粉酶 多孔淀粉 氨茶碱 紫外分光光度法 

分 类 号：TS231[轻工技术与工程—粮食、油脂及植物蛋白工程] TQ432.2[轻工技术与工程—食品科学与工程]