湖南、湖北等省成年人膳食锌吸收率分析  

Determination of diet zinc absorption rate for adults in cities of south China

作　　者：刘小立[1] 张慧敏 王瑞[3] 徐健[1] 王舟 崔晞[4] 杨晓光[5] 

机构地区：[1]广东省深圳市慢性病防治院,518021 [2]广东省深圳市疾病控制中心 [3]华中科技大学同济医学院公共卫生学院 [4]山东大学公共卫生学院 [5]中国疾病预防控制中心营养与食品安全所

出　　处：《中国公共卫生》2008年第9期1132-1134,共3页Chinese Journal of Public Health

基　　金：国家自然科学基金重点项目(39930150;2000-2004)

摘　　要：目的评价我国湖南、湖北等省成年人膳食结构中Zn的吸收率,为我国不同人群、不同膳食结构的Zn吸收率研究提供参考资料。方法采用67ZnSO4锌稳定性同位素示踪法,以稀土元素镱(Yb)为粪便回收标记物,进行现场人体代谢实验。受试者为健康成年男子和育龄妇女各10名,一次性口服4.00 mg67ZnSO4和1.00mg YbCl3,粪便监测法收集排出粪样;电感耦合等离子体质谱仪(ICP-MS)测定粪样中67Zn/66Zn比值,原子吸收火焰分光光度法(AAS)测定粪样总Zn,计算膳食Zn吸收率。结果在不同膳食结构下,成年男子Zn表观吸收率为28.4%,真吸收率为30.3%;育龄妇女Zn表观吸收率为26.8%,真吸收率为30.9%。结论湖南、湖北等省份膳食结构中Zn的吸收率高于我国现行Zn的膳食营养参考摄入量(DRIs)(25%的估计值)。Objective To evaluate the diet zinc（Zn） absorption rate in the urban adults of south China（Hunan and Hubei province） and to provide reference data to the absorption rate of Zn in different people with various dietary patterns in China. Methods We performed human metabolism experiment by enriched stable isotope ^67Zn tracer method with ^67ZnSO4 as tracer and rare earth element ytterbium（Yb） as marker indicating the recovery. Ten healthy men and ten women were recruited to take 4.00 mg Zn tracer and 1.0 mg Yb orally once. Fecal samples were collected by fecal monitoring. The isotope ratio of ^67 Zn/^66Zn was measured by inductive couple plasma mass spectrometry（ ICP - MS）, and total Zn was detected by atomic absorption spectrometry（AAS）. Results The apparent absorption rate of Zn in men was 28.4 %, while true absorption rate was 30.3 %, and in women was 26.8 % and 30.9 % respectively. Conclusion The absorption rate of diet Zn in urban adults of south China was higher than that of Chinese Dietary Reference Intakes（DRIs） of Zn（about 25 % ）.

关 键 词：南方城市 膳食锌 稳定性同位素 吸收率 

分 类 号：R151.3[医药卫生—营养与食品卫生学]