奇可力多糖抗衰老作用的实验研究  

Experimental Study on Anti-aging Effect of Chicory Polysaccharides

作　　者：戚颖欣[1] 曹柏营[1] 郑鸿雁[2] 昌友权[1] 

机构地区：[1]吉林工程技术师范学院生物与食品工程系,吉林长春130052 [2]吉林农业大学食品科学与工程学院,吉林长春130118

出　　处：《食品科学》2008年第9期564-566,共3页Food Science

基　　金：吉林省教育厅资助项目(吉教合字2007第413号)

摘　　要：目的:观察奇可力多糖(CPS)的抗衰老作用。方法:奇可力粗多糖按100、200、400mg/kg连续灌胃3～7d,观察小鼠的存活时间,连续游泳时间和免疫器官重量实验。大鼠连续灌胃20d,测血清LPO含量和SOD活性。结果:奇可力多糖能明显提高小鼠耐氧及抗疲劳能力,增加正常小鼠免疫器官重量,并明显增强小鼠网状内皮系统的吞噬功能。可明显降低老年大鼠血清过氧化脂质(LPO)含量,提高超氧化物歧化酶(SOD)活性。结论:奇可力多糖具有抗衰老作用。Objective： To evaluate anti-aging effect of chicory polysaccharides（CPS）. Methods： After mice were treated with CPS 100, 200, 400 mg/kg by oral administration for 3-7 days continually, the survival time, swimming time and weight of immune organ were investigated. After the aged rats were treated by oral administration for 20 days, the content of serum LPO and the activity of SOD were determined. Results： CPS can obviously enhance the anti-fatigue and the hypoxia to lerance ability, increase the weight of immune organ and improve the macrophage function of the mice. In addition, CPS also can significantly decrease the content of serum LPO and increase the activity of SOD of the aged rats. Conclusion： The results indicated that CPS has anti- aging effect.

关 键 词：奇可力多糖 抗衰老:免疫吞噬系统功能:血清过氧化脂质 超氧化物歧化酶 

分 类 号：Q539[生物学—生物化学]