缺氧缺血性脑病新生儿血清肌钙蛋白Ⅰ和乳酸的变化  

Serum cardiac troponin Ⅰ and lactic acid in neonatal patients with hypoxic-ischemic encephalopathy

作　　者：郭东杰[1] 安国瑞[1] 王玉芬[1] 王华忠[2] 刘海滨[1] 

机构地区：[1]河北省沧州市中心医院检验科,061001 [2]河北省黄骅市人民医院

出　　处：《中华全科医师杂志》2008年第10期714-715,共2页Chinese Journal of General Practitioners

摘　　要：检测128例缺氧缺血性脑病新生儿和38例健康新生儿的血清肌钙蛋白Ⅰ和乳酸。新生儿缺氧缺血性脑病组血清肌钙蛋白Ⅰ明显升高，与健康新生儿比较差异有统计学意义（t=2．56，P〈0．05），重度缺氧缺血性脑病患儿与轻度缺氧缺血性脑病患儿血清肌钙蛋白Ⅰ比较差异有统计学意义（t=2．32，P〈0．05）。血清肌钙蛋白Ⅰ和乳酸是心肌损伤和缺氧程度的敏感指标之一，对于病情的判断具有重要意义。Serum Cardiac troponin I （cTn I ） and lactic acid were measured in 128 neonatal patients with hypoxic-ischemic eneephalopathy and 38 healthy neonates （control group）. Serum eTn I and lactic acid levels were higher in neonates with hypoxic-isehemie eneephalopathy than those in healthy neonates （P 〈 0.05 ）; and the differences of these values were also statistically significant between the serious patients and the mild patients （P 〈 0. 05 ）. Serum cTn I and lactic acid are two sensitive markers for degree of myocardial injury and hypoxia in neonatal patients with hypoxic-isehemic encephalopathy.

关 键 词：缺氧缺血 脑 肌钙蛋白Ⅰ 乳酸 

分 类 号：R742[医药卫生—神经病学与精神病学]