益生菌对大鼠血脂和免疫功能影响的实验研究  

Experimental study on the impact of probiotic bacteria on blood lipids and immune

作　　者：李智生[1] 于萍[1] 王景明[1] 张蕴奎[1] 李秀霞[1] 郝玉美[1] 刘洪琪[1] 

机构地区：[1]潍坊学院医院潍坊市人民医院,山东省潍坊261061

出　　处：《中国基层医药》2008年第9期1470-1471,共2页Chinese Journal of Primary Medicine and Pharmacy

基　　金：山东省维坊市2007年科学技术发展计划（200702057）

摘　　要：目的研究益生菌对大鼠血脂和免疫功能的影响。方法用高脂饲料喂养大鼠，以洛伐他汀为阳性对照物，以不同种益生菌喂养实验组大鼠，在实验开始前和实验开始后30d时检测各组大鼠血清TC、TG和免疫指标，与对照组比较。结果益生菌喂养组大鼠与对照组大鼠比较，益生菌喂养组大鼠血中TC及TG均明显低于对照组（P〈0．01），免疫指标明显高于对照组（P〈0．05）。结论益生菌明显降低益生菌喂养组大鼠血中的TC、TG，而且提高益生菌喂养组大鼠的免疫功能。Objective To study the influence of probiotic bacteria on rats blood lipids and immune function. Methods Rats fed with high fat diet, as a positive control of lovastatin in different kinds of experimental rats fed with probiotic bacteria. Before the experiment and 30 days after the experiment, the serum TC, TG and immune indicators were examined, compared with the control group. Results Probiotic bacteria feeding rats compared with con- trol group rats, TC and TG in probiotic bacteria feeding rats blood are obviously lower than the controled group, （ P 〈 0. 01 ）, the immune index is obviously higher than the control group （ P 〈 0. 05 ）. Conclusion Probiotic bacteria ob- viously reduces TC and TG in Probiotic feeding rats blood, and improves the immunological function of probiotie bacteria feeding rats.

关 键 词：嗜酸乳杆菌 血脂异常 免疫测定 洛伐他汀 大鼠 

分 类 号：R15[医药卫生—营养与食品卫生学]