纳豆菌蛋白酶水解玉米醇溶蛋白制备血管紧张素转化酶抑制肽  

Preparation of angiotensin converting enzyme inhibitory peptides after hydrolysis of zein catalyzed by the proteases of Bacillus natto

作　　者：芦明春[1] 刘波[1] 郭雨时[1] 李志锐[1] 金风燮[1] 

机构地区：[1]大连工业大学生物与食品工程学院,辽宁大连116034

出　　处：《中国酿造》2008年第12期7-9,共3页China Brewing

基　　金：国家自然科学基金资助项目(30371744);辽宁省教育厅资助项目(2005015)

摘　　要：利用纳豆菌固态发酵产酶酶解玉米醇溶蛋白,酶解物经SephadexG-25分离纯化,对产物及其组分血管紧张素转化酶(ACE)抑制活性进行检测。结果表明,酶解血管紧张素转化酶的抑制活性为77.83%,经分离后组分3的抑制效果最好,可达89.4%。Zein was hydrolyzed by the proteases produced by Bacillus natto in solid fermentation. The hydrolysates were separated and purified by sephadex G-25. The inhibitory activity of zein hydrolysates to angiotensin converting enzyme （ACE） were detected. The results showed that the inhibitory activity of zein hydrolysates to ACE was 77.83%. After separation, the component 3 displayed the highest inhibitory activity of 89.4%.

关 键 词：血管紧张素转化酶 玉米醇溶蛋白 纳豆菌 抑制性 

分 类 号：TQ464.7[化学工程—制药化工]