Synthesis and Steric Structure of 1, 5-Benzothiazepine-Phenyl-β-Lactams  

作　　者：Yuan LI Jian Dong SHI Yuan Jing ZHANG  Sheng JIN Qi Yi XING(Department of Chemistry, Hebei Normal University. Shijiazhuang 050016 ShijiazhuangTeachers College 050041)(Beliing institute of Radiation Medicine, Beijing 100850)(Institute of Chemistry and 

出　　处：《Chinese Chemical Letters》1999年第1期23-26,共4页中国化学快报（英文版）

摘　　要：1, 5-Benzothiazepines 1 react with phenylacetyl chloride to give the title compounds.The structures of these new compounds were confirmed by elemental analysis, ~1H NMR, ^(13)C NMRand MS spectroscopy, and their configuration (the mutual positions of the substituents relative to theβ-lactam ring) and conformation of the compounds were determined by X-ray crystal analysis.1, 5-Benzothiazepines 1 react with phenylacetyl chloride to give the title compounds.The structures of these new compounds were confirmed by elemental analysis, ~1H NMR, ^(13)C NMRand MS spectroscopy, and their configuration (the mutual positions of the substituents relative to theβ-lactam ring) and conformation of the compounds were determined by X-ray crystal analysis.

关 键 词：1 5-BENZOTHIAZEPINE Β-LACTAM stereospecific reaction 

分 类 号：O623.73[理学—有机化学]