云南高校图书馆联盟文献共享服务平台- 1,5-BENZOTHIAZEPINE

1,5-BENZOTHIAZEPINE: 作品数：14被引量：10H指数：2; 导出分析报告; 相关领域：理学更多>>; 相关作者：王兰芝更多>>; 相关机构：河北师范大学更多>>; 相关期刊：《Chemical Research in Chinese Universities》《Chinese Journal of Structural Chemistry》《Chinese Journal of Chemistry》《Chinese Chemical Letters》更多>>; 相关基金：国家自然科学基金河北省自然科学基金教育部留学回国人员科研启动基金更多>>

Structure-Activity Relationship, Cytotoxicity and Mode of Action of 2-Ester-substituted 1,5-Benzothiazepines as Potent Antifungal Agents被引量：1: 《Chinese Journal of Chemistry》2013年第10期1305-1314,共10页Wang Kang Xingqiong Du Lanzhi Wang Lijuan HU Yuhuan Dong Yanqing Bian Yuan Li; Acknowledgement The authors gratefully acknowledge the financial support of the National Natural Science Foundation of China （No. 20972040）.; Our studies examined the structural features responsible for the antifungal activity of 2-ethoxycarbonyl-1,5- benzothiazepine （7a）. Three series of 1,5-benzothiazepine derivatives were synthesized and screened for t...; 关键词：1 5-benzothiazepines antifungal agents antifungal mechanism CYTOTOXICITY structure-activity relationships

The synthesis and biological evaluation of a series of novel 2-COOC_2H_5/COONa substituted 1,5-benzothiazepine derivatives as antimicrobial agents被引量：4: 《Chinese Chemical Letters》2009年第6期660-662,共3页Ping Zhang Lan Zhi Wang Hui Shu Wu Jia Ming Lan Yuan Li Yong Xiang Wang; support from National Natural Science Foundation of China(No.20772021);the Natural Science Foundation of Hebei Province,China(No.2007000239); A series of novel 1,5-benzothiazepine derivatives containing COOC2H5/COONa groups at the C（2）-position were synthesized and evaluated for their antifungal and antibacterial activities by both disc diffusion and mini...; 关键词：1 5-BENZOTHIAZEPINE ANTIFUNGAL Antibacterial activities

Synthesis and Crystal Structure of 2-p-Methyloxyphenyl- 3a-(2-phenyl-1,2,3-triazole-4-yl)-3,4-dihydro-1,2,4- oxa-diazolo[4,5-d][1,5] Benzothiazepine: 《Chinese Journal of Structural Chemistry》2007年第9期1061-1065,共5页徐峰刘方明沈良刘罡杨春陈遒; This work was supported by the National Natural Science Foundation of China (No. 29702007 and 20162004); The title compound2-p-methyloxyphenyl-3a-（2-phenyl-1,2,3-triazole-4-yl）-3,4- dihydro-1,2,4-oxa-diazolo[4,5-d][1,5] benzothiazepine （C31H25N5O2S, Mr = 531.63） has been synthesized and its structure was determined b...; 关键词：1 5-BENZOTHIAZEPINE 2-phenyl-1 2 3-triazole 1 2 4-oxadiazole crystal structure

Further Investigation on the Rearrangement Mechanism of Reactions of 1,5-Benzothiazepines with Ethoxycarbonylcarbene: 《Chemical Research in Chinese Universities》2006年第1期36-39,共4页WU Chun-zan HUANG Jia-xing ZHANG Qi-han XU Jia-xi; SupportedpartlybytheNationalNaturalScienceFoundationofChina(Nos.20272002and20472005),MinistryofEducationofP.R.China(SRFforROCSandEYTP)andPekingUniversity(PresidentGrant).; The reactions of 2,3-dihydro-1,5-benzothiazepines with ethoxyearbonylcarbene undergo complex rearrangements to produce rlng-opening and ring contraction products. Previously it was presumed that the different products...; 关键词：1 5-BENZOTHIAZEPINE Ethoxycarbonylcarbene REARRANGEMENT RING-CONTRACTION RING-OPENING

Differentiation of Constitutional Isomer of 2,2a,3,4-Tetrahydro- 4-methyl-2a-phenyl-2-(thiophen-2-yl)-1H-azeto[2,1-d][1,5] benzothiazepin-1-one-5-oxide and Fragmentations of 2,3-Dihydro- 2,4-diphenyl-1,5-benzothiazepine-1-oxide/-1,1-dioxide被引量：2: 《Chemical Research in Chinese Universities》2005年第3期274-279,共6页XUJia-xi ZUOGang LIANGBo; SupportedbytheNationalNaturalScienceFoundationofChina(No.20272002).; Mass spectrometric behaviour of 2,2a,3,4-tetrahydro-4-methyl-2a-phenyl-2-(thiophen-2-yl)-1H-azeto[2,1-d][1,5]benzothiazepin-1-one-5-oxide and 2,3-dihydro-2,4-diphenyl-1,5-benzothiazepine-1-oxide/-1,1-dioxide have been...; 关键词：1H-Azeto[2 1-d][1 5]benzothiazepin-1-one 1 5-BENZOTHIAZEPINE LACTAM Mass spectrometry

Synthesis and Crystal Structure of an (N-Protected amino)-β-lactam Derivative of 1,5-Benzothiazepine: 《Chinese Journal of Structural Chemistry》2002年第2期133-135,共3页张萍李旭张丽君李媛; Supported by the Natural Foundation of Hebei Province; The title compound -(N-protected amino)--lactam (C36H33N2O5ClS), derivative of 1,5-benzothiazepine, was prepared by the reaction of 1,5-benzothiazepine 1 with (4R)- phenyloxazolidylacetyl chloride and characteized by ...; 关键词：1 5-BENZOTHIAZEPINE -LACTAM CYCLOADDITION crystal structure

Spectral and Mechanistic Studies of the Reactions of Substituted 1,5-Benzothiazepine with Dichloroacetyl Chloride and Triethylamine: 《Chinese Chemical Letters》2001年第10期851-854,共4页Xin ZHOU Shrong Shi LIN Jin Fang YUAN Zhe Ming WANG Hong Zhong WANG; This work was supported by the National Natural Science Foundation of China (No. 29972001).; A [2+2] cycloaddition adduct 2 and a novel ring-opening product 3 were obtained from the reactions of 2,3-benzothiazepines 1 with dichloroacetyl chloride and triethylamine. The relative ratios of 2 and 3 were affected...; 关键词：BENZOTHIAZEPINE dichloroacetyl chloride cycloaddition adduct ring-opening product

Synthesis and Stereostructure of New β-Lactam Derivatives of1,5-Benzothiazepines: 《Chinese Chemical Letters》1999年第6期447-448,共2页Yuan LI Na SUN Sheng JIN(Department of Chemistry Hebei University Shijiazhuang 050016 Institute of Chemistry and Molecular Engineering Peking University Beijing 100871); Reaction of 1,5-benzothiazepine with N-protected glycine gives new a-amino-β-lactamderivatives of 1.5-benzothiazepine. The configuration and conformation of the products wereconfirmed by x-ray diffraction. The resu...; 关键词：1.5-Benzothiazepine Β-LACTAM stereospecific reaction

Synthesis and Steric Structure of 1, 5-Benzothiazepine-Phenyl-β-Lactams: 《Chinese Chemical Letters》1999年第1期23-26,共4页Yuan LI Jian Dong SHI Yuan Jing ZHANG Sheng JIN Qi Yi XING(Department of Chemistry, Hebei Normal University. Shijiazhuang 050016 ShijiazhuangTeachers College 050041)(Beliing institute of Radiation Medicine, Beijing 100850)(Institute of Chemistry and; 1, 5-Benzothiazepines 1 react with phenylacetyl chloride to give the title compounds.The structures of these new compounds were confirmed by elemental analysis, ~1H NMR, ^(13)C NMRand MS spectroscopy, and their config...; 关键词：1 5-BENZOTHIAZEPINE Β-LACTAM stereospecific reaction

Synthesis and Crystal Structure of a β-Lactam Derivative of 2,4-Diaryl-1,5-Benzothiazepine: 《Chinese Journal of Structural Chemistry》1999年第1期59-62,共4页LI Yuan DU Cai Yun YANG Qiu Qing; The compound(2) (C 24 H 20 NO 2ClS)(see Scheme 1) has been synthesized by reaction of 1, 5 benzothiazepine with chloroacetyl chloride and crystallized in the monoclinic system, space group P2 1/c, a=12.54...; 关键词：crystal structure cycloaddition reaction β lactam 1 5 benzothiazepine

1,5-BENZOTHIAZEPINE