肿瘤患者抗坏血酸水平的初步研究  

Preliminary study on the ascorbic acid level of tumor patient

作　　者：蔡桦[1] 曾卫[1] 张顺[1] 

机构地区：[1]湖北省肿瘤医院,430070

出　　处：《中国肿瘤临床与康复》1998年第S1期11-12,共2页Chinese Journal of Clinical Oncology and Rehabilitation

摘　　要：目的：为探讨恶性肿瘤患者抗坏血酸水平的变化。方法：对106例肿瘤病人及50例健康人做了血浆抗坏血酸浓度的检测。结果：健康人血浆抗坏血酸均值为7．6±1．4mg／L（X±S）；肝癌、肺癌、乳腺癌、鼻咽癌患者抗坏血酸水平均低于健康人（P＜0．01～0．05；而胃癌、直结肠癌、恶性淋巴瘤及多发性骨髓瘤患者与健康人比较，则无明显差异（P＞0．05）。结论：提示在肿瘤的发生、发展过程中，癌细胞的代谢使抗坏血酸消耗增加。而抗坏血酸的抗肿瘤作用又与肿瘤的类型及肿瘤组织对放射线的敏感性有关。常?In order to explore the change of the ascorbic acid level in malignant tumor patients ， We detected the plasma ascorbic acid of 106 cases tumor patients and 50 cases normal people. The results indicate that the average level of ascorbic acid in normal people was 7. 6± 1. 4.mg/L (X±S). The level of acorbic acid in the patient of liver cancer were also below that of normal people (P＜0.01-0. 05. But contrast with normal people,the asorbic acid level of patients which have gastric cancer、colorectal cancer malignant lymphoma and multiple myeloma had not significant change (P>0. 05). These infer that in the course of tumorigenesis and tumor development, the metabolism of tumor cells increased the consumption of adcorbic acid, and the anti-tumor effect of ascorbic acid had relation to the type of tumor and the sensitivity of tumor tissue to the radioactive rays.〔

关 键 词：肿瘤 抗坏血酸 

分 类 号：R730.4[医药卫生—肿瘤]