Experimental studies on gene transfer into hematopoietic stem cells mediated by liposome and the influence of expansion on gene expression  

Experimental studies on gene transfer into hematopoietic stem cells mediated by liposome and the influence of expansion on gene expression

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作  者:Hua-Zhong Lu, Ping Zou, Chong-Yu Li, Zhi-Fu Xiang Hematology Institute, Tongji Medical University, Wuhan430022 

出  处:《中国实验血液学杂志》1997年第3期326-326,共1页Journal of Experimental Hematology

摘  要:Liposomes have several advantages over viral vectorsfor gene delivery both in vitro and in vivo. However,few data are available concerning gene transfer intohematopoietic stem cells. In order to explore theefficiency and the stability of expression of gene transferinto hematopoietic stem cells, we have transduced twomarker genes (Neo^R and Lac Z) co-transfer into humanbone marrow CD34^+ hematopoietic stem cells

关 键 词:HEMATOPOIETIC LIPOSOME concerning COLONY expanded MARKER remarkably stain 

分 类 号:R329[医药卫生—人体解剖和组织胚胎学]

 

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