创伤后应激障碍的诊断与治疗  

Diagnosis and treatment of post-taumatic stress disorder

作　　者：徐俊冕[1] 

机构地区：[1]复旦大学附属中山医院心理医学科,上海200032

出　　处：《世界临床药物》2009年第4期196-200,共5页World Clinical Drug

摘　　要：创伤后应激障碍(PTSD)是常见、反复发作的慢性精神障碍,常伴有抑郁、焦虑、心身障碍与药物滥用,有较高的自杀率与功能损害。至今,人们对PTSD的概念仍有很多误解,诊断也存在许多困难。近十多年来,PTSD在神经生物学方面有了更多新发现,同时由于认知行为治疗和选择性5-羟色胺再摄取抑制剂(SSRI)的研究进展,以往对PTSD预后的悲观估计已得到改变,临床患者症状完全缓解或大部分消除及功能康复是可期待的。Post-taumatic stress disorder （PTSD）is a common, chronic and recurrent attacks mental disorder with high suicide rate and social occupational dysfunctions. The common comorbid disorders of which are depression, other anxiety disorders, psychosomatic disorders and substance abuse. Misunderstandings on the concept of PTSD still exist and there are a lot of difficulties in the diagnosis of PTSD. In recent 10 years, studies on neurobiology of PTSD show much more findings. Since the developments of cognitive behavior therapy and selective serotonin reuptake inhibitors, the pessimistic view about outcome of PTSD has already changed. Remission or elimination of the most symptoms of PTSD and functional rehabilitation may be exoectant.

关 键 词：创伤后应激障碍 诊断 神经生物学 选择性5-羟色胺再摄取抑制剂 

分 类 号：R749.72[医药卫生—神经病学与精神病学]