摄食鱿鱼对小鼠脂质代谢影响的研究  

Effects of dietary squid on lipids metabolism in mice

作　　者：任兵兴[1] 王玉明[1] 胡晓倩[1] 王静凤[1] 薛长湖[1] 

机构地区：[1]中国海洋大学食品科学与工程学院,山东青岛266003

出　　处：《南方水产》2009年第3期41-45,共5页South China Fisheries Science

基　　金：国家科技支撑计划项目(2008BAD94B05);农业部"948"项目[2006-G41(3)]

摘　　要：用含10%鱿鱼、猪肉或鸡卵蛋白配制的标准饲料或高胆固醇饲料来喂食小鼠,称量小鼠体重、肝脏、肾脏重量以及精巢脂肪重量,评价不同蛋白质对小鼠成长的影响。测定小鼠的血清总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白和肝脏TC、TG及磷脂(PL)含量,比较鱿鱼和其他蛋白质对小鼠脂肪代谢的影响。结果显示,鱿鱼作为一种优质蛋白质能明显降低正常小鼠和高胆固醇血症模型小鼠的血清总脂水平(P<0.05)以及动脉粥样硬化指数(AI)(P<0.05),虽然对正常小鼠的肝脂水平有一定的升高作用,但对高胆固醇血症小鼠的肝脏脂肪浓度未见显著影响。因此,鱿鱼虽然是高胆固醇食品,但具有较高的营养价值,且可能对由高胆固醇血症引发的动脉粥样硬化不具有危害。In order to compare the effects of squid, pork and egg on lipids metabolism, 10% squid, pork or egg protein was added to normal and high-cholesterol diet to feed mice. The concentrations of serum total cholesterol （TC）, triglycerides （TG）, high-density lipoprotein and liver TC, TG, phospholipids contents of mice were measured. In order to observe the effects of dietary squid, pork and egg on the growth of mice, the body weight gain, liver and kidney weight, and testis adipose tissue weight were measured. As a result, squid as a high-quality protein decreased serum total lipid levels and atherosclerosis index （AI） in normal and hypercholesterolemia mice significantly （ P 〈 0. 05 ）. Feeding squid increased hepatic lipid levels of normal mice but did not affect that of hypercholesterolemia mice. In conclusion, the squid as a kind of high-cholesterol food did not increase the risk of atherosclerosis induced by hypercholesterolemia.

关 键 词：鱿鱼 胆固醇 甘油三酯 动脉粥样硬化 

分 类 号：R589.2[医药卫生—内分泌]