生物阻抗方法评价糜烂性胃炎患者胃动力  

Detection and evaluation of gastric motility for the patients with erosive gastritis through bio-impedance

作　　者：阳家长 李章勇[2] 刘纯伦[3] 方晓杰[3] 

机构地区：[1]重庆市永川区人民医院,402160 [2]重庆邮电大学生物医学工程研究中心,400065 [3]重庆医科大学附属第一医院,400016

出　　处：《重庆医学》2009年第11期1356-1358,共3页Chongqing medicine

基　　金：重庆市卫生局科技项目(2008-2-92)

摘　　要：目的采用生物阻抗胃动力检测和评价方法研究糜烂性胃炎患者胃动力电-机过程变化和影响因素,以选择糜烂性胃炎的胃动力特征参数。方法信号检测设备和处理软件系统由重庆邮电大学研制。筛选30例糜烂性胃炎患者,通过谱分析方法,根据主能量和支配频率将信号分类。胃电信号和胃阻抗信号频率、功率谱、动态谱、节律、正常胃电和胃阻抗节律的功率等参数由系统提供。结果患者胃动力参数,2-4CPM功率比例为59.2±4.4,频率百分比为70.4±25.5,频率变异系数为0.182±0.059,功率变异系数为1.576±0.481,与健康人群比较差异有统计学意义(P<0.05)。用药1周后患者主述症状还没有缓解或消除,但患者胃电功率和频率变异系数前后对比变化有统计学意义(P<0.05),来源于阻抗信号的胃动力参数有变化趋势,但差异无统计学意义(P>0.05)。结论实验结果表明胃阻抗和同步胃电信号测量的综合应用可能提供一种无创技术来研究和估计与糜烂性胃炎的生理和病理学情况一致的胃动力状况。Objective In order to investigate the complex course of electricity and mechanism of erosive gastritis（EG） and the influences of them,it is neccesery to extract gastric motility feature indexes. Methods 30 volunteers of erosive gastritis were select ed. The signal processing device was designed by Chongqing University of Posts and Telecommunications..By the means of spectrum analysis technic,the signals could be classify according to the dominant power and dominant frequency. Some indexes such as fre quency of EGG and IGM, signal power spectrum and dynamic spectrum, the rates of rhythm and power for the normal EGG and IGM and so on could also be calculated. Results The power ratio in 2-4CPM was 59.2± 4.4, the frequency ratio was 70.4± 25.5, the frequency instability coefficient was 0. 182±0. 059, and the power instability coefficient was 1. 576 ±0.481. The parameters had changed signifcantly between health adult and patient（P〈0.05）. The experiments of gastric motility measurement and evaluation were executed including before teating and after a week. The volunteers feel that the symptom was not disappeared. The feature of electrogastrogram had changed significantly（such as power instability coefficient, frequency instability coefficient P〈0.05）, otherwise those of impedance signal had not（P〉0.05）. Conclusion The results of the experiments show that the method based on the synchronous measurement of EGG and IGM can provide a non-invasive way to investigate and evaluate erosive gastritis corresponding to gastrointestinal physiology and pathology conditions.

关 键 词：糜烂性胃炎 胃动力 胃阻抗 多分辨分析 胃电 

分 类 号：R573.3[医药卫生—消化系统] R318.01[医药卫生—内科学]