3-醛基水杨酸缩氨基硫脲希土配合物的合成、表征及抑菌活性研究  

STUDIES ON THE SYNTHESIS, CHARACTERIZATION AND BACTERIOSTATICACTIVITY OF 3FORMYLSALICYLIC ACID THIOSEMICARBAZONE AND ITS RARE EARTH COMPLEX

作　　者：周毓萍[1] 于红娟 杨正银[1] 杨汝栋[1] 

机构地区：[1]兰州大学化学系

出　　处：《无机化学学报》1998年第2期162-167,共6页Chinese Journal of Inorganic Chemistry

摘　　要：新配体３－醛基水杨酸缩氨基硫脲（简称ＨＬ），由３－醛基水杨酸和氨基硫脲合成。并用此配体与三价希土醋酸盐反应，合成了９个组成为［ＲＥＡｃ２Ｌ］·ｎＨ２Ｏ（ＲＥ＝Ｙ、Ｌａ、Ｎｄ、Ｓｍ、Ｅｕ、Ｇｄ、Ｈｏ、Ｅｒ、Ｙｂ，ｎ＝２～４）的新配合物。所有化合物均经元素分析、ＩＲ、ＵＶ、摩尔电导。１ＨＮＭＲ和差热—热重分析等表征，并对配体和配合物的抑菌活性进行了测试。A new ligand, 3formylsalicylic acid thiosemicarbazone has been synthesized by the reaction of 3formylsalicylic acid with thiosemicarbazide. Its nine rare earth complexes have been prepared by reacting the ligand with REAc 3·nH 2O in methanol. The complexes have been characterized by elemental analyses, molar conductivities, IR, UV, 1H NMR and DTATG. The composition of these complexes is determined as ·nH 2O (RE=Y, La, Nd, Sm, Eu, Gd, Ho, Er, Yb. n=2￣4). The synthesized ligand and its complexes have been evaluated for bacteriostatic activity against Escherichia Coli, Staphylococcus aureus and Bacillus subtilis.

关 键 词：醛基水杨酸 缩氨基硫脲 稀土 配合物 抑菌活性 

分 类 号：O614.33[理学—无机化学]