复合不饱和脂肪酸对人血脂的影响  

Effect of Polyunsaturated Fatty Acids on Serum Lipid of Human

作　　者：徐增康[1] 张颖[1] 

机构地区：[1]陕西省疾病预防控制中心,陕西西安710054

出　　处：《实用预防医学》2009年第4期1103-1105,共3页Practical Preventive Medicine

摘　　要：目的研究复合多不饱和脂肪酸的降血脂作用。方法将102名自愿受试者按血清总胆固醇(TC)随机分为试食和对照组,试验组给予每日3次,每次1粒复合不饱和脂肪酸,45d后取血,检测血TC、甘油三酯(TG)、血高密度脂蛋白胆固醇(HDL-C)。结果实验结束后,试验组与对照组相比,血清TC水平降低0.65mmol/L,血清TG水平降低0.31mmol/L,血清HDL-C水平上升0.24mmol/L,差异均有统计学意义(P<0.01)。试验组自身比较,试验后血清TC水平降低0.80mmol/L,血清TG水平降低0.40mmol/L,血清HDL-C水平上升0.14mmol/L,差异均有统计学意义(P<0.01)。试验组血清TC、TG、HDL-C有效率分别为76.5%、78.4%、80.4%,差异均有统计学意义(P<0.01)。结论复合多不饱和脂肪酸辅助降血脂人群实验阳性,复合多不饱和脂肪酸具有辅助降血脂功能。Objective To analyze the effect of polyunsaturated fatty acid （PUFA） on lipid metabolism. Methods Totally 102 volunteers were randomly assigned into the trial group and the control group according to total cholesterol level in the serum, everyone in the trial group was given one PUFA pill a time and three times a day. After 45 days, blood samples were collected and analyzed. Results The TC level of the trial group decreased 0.65 mmol/L compared with that of the control group, and the TG level decreased 0.31 mmol/L, but the HDL- C level increased 0. 24 mmol/L; there were statistically significant differences in the levels of TC, TG, and HDL - C between the two groups （P〈0.01）. Comparison made with the trial group itself before and after the experiment indicated that thelevels of TO and TG decreased significantly by 0.80 mmol/L and 0.40 mmol/L, respectively, but the HDL - C level increased significantly by 0.14 mmol/L after trial, and the difference was statistically significant （P〈 0.01）. The effective rates of TO, TG and HDL - C of the trial group were 76.5 %, 78.4%, and 80.4%, respectively; and the difference was statistically significant （P〈0.01）. Conclusion Polyunsaturated fatty acid has an adjusting effect on blood lipids in human being.

关 键 词：多不饱和脂肪酸 高血脂 影响 

分 类 号：R151[医药卫生—营养与食品卫生学]