纽甜及其中间体3,3-二甲基丁醛的新合成方法  

Novel synthetic methods for Neotame and 3,3-dimethyl butyraldehyde

作　　者：吴金山 袁赛勇[2] 颜士飞[2] 

机构地区：[1]盐城捷康三氯蔗糖制造有限公司,江苏盐城224300 [2]东南大学化学化工学院,江苏南京211189

出　　处：《化工时刊》2009年第7期16-19,共4页Chemical Industry Times

摘　　要：采用负载金属氧化物催化剂多相催化合成3,3-二甲基丁醛,在Pd/C催化下与阿斯巴甜加氢反应生产纽甜。该方法合成3,3-二甲基丁醛工艺简单、后处理简便、环境污染小,合成纽甜产物纯度高。Afforded metal oxides were used as catalysts to synthesize 3,3 - dimethyl butyraldehyde, followed reacted it with aspartame to yield neotame. The process of chemical synthesis and late treatment of 3,3 - dimethyl butyraldehyde were simple, the environment pollution was less. The high purity neotame product was gained.

关 键 词：纽甜 3 3-二甲基丁醛 阿斯巴甜 催化氧化 

分 类 号：TQ224.12[化学工程—有机化工]