学龄儿童维生素A、C、E摄入量与免疫水平关系  

Assessment on vitamin A,C,E intake and immune function in school-age children

作　　者：唐咏梅[1] 朱骄锋[1] 周会[1] 马海英[1] 

机构地区：[1]华北煤炭医学院预防医学系河北省煤矿卫生与安全实验室,唐山063000

出　　处：《中国公共卫生》2009年第8期937-939,共3页Chinese Journal of Public Health

基　　金：河北省医科科学研究重点课题计划项目(08178)

摘　　要：目的了解学龄儿童维生素A、C、E摄入水平、免疫指标水平及其相关关系。方法选取1～6年级学生293人进行食物摄取频率和膳食调查,对家长知情同意的262人采静脉血测定血浆维生素、全血T淋巴细胞亚群和血清白细胞介素-2(IL-2)、免疫球蛋白。结果学龄儿童维生素A、C、E摄入量与其血浆含量均呈正相关;维生素A、C、的平均摄入量低于推荐摄入量(RNI),摄入不足RNI的分别占52.62%和35.59%,血浆缺乏率分别为11.1%和15.3%,亚临床缺乏率分别为29.0%和21.4%;维生素E的摄入量高于适宜摄入量(AI),血浆水平低于参考值的占9.92%。儿童各免疫指标中,CD3+细胞百分比、CD4+/CD8+、IL-2和IgA水平低于参考值,IL-2、CD3+、CD4+、CD4+/CD8+和IgG、IgA、C3低于参考值范围分别占54.96%,22.14%,37.79%,29.41%和17.18%,22.52%,5.73%;CD8+和IgM高于参考值者分别占23.66%和12.60%。维生素A摄入量与IL-2、CD4+、CD4+/CD8+和IgG呈正相关,与IgM呈负相关;维生素C摄入量与CD3+、CD4+/CD8+和IgA呈正相关,与IgM呈负相关;维生素E摄入量与IL-2、CD4+和IgG呈正相关。结论学龄儿童维生素A、C营养水平较低,维生素A、C、E摄入量与免疫指标水平有相关性。Objective To study the correlation between the intakes of vitamin A,C, E and the immunization indicators among childeren. Methods The five days diet and one month food intake frequency of 293 primary school children were investigated. Plasma vitamin, T-lymphocyte subsets and serum IL-2, IgG; IgM, IgA, complement C3 were determined in 262 of the children. Results The children＇s intakes of vitamin A, C, E have a positive correlation with plasma levels of vitamins. The average intakes of vitamin A,C were lower than recommended intake（RNI） with inadequate rates of 52. 62% and 35.59%. The rates of deficiency and marginal deficiency for vitamin A were 11.1% and 29. 0% ;that of for vitamin C were 15. 3% and 21.4%. Although the vitamin E intakes in children was high,there were still 9. 92% of the children with the plasma level lower than the normal range. The percentages of CD3＊ cells,the ratio of CD4^＋/CD8^＋ ,as well as IL-2,IgA were below the reference value. The rates of lowere level CD3^＋, CD4^＋ , CD4^＋/CD8^＋, IL-2, as well as IgG, IgA, Ca than the refernce value were 29.41% ,54. 96% ,22. 14% ,37.79% ,17. 18% ,22. 25% and 5.73% ,respectively. The CD8^＋ ,IgM levels higherthan the reference value were observed in 23.66% and 12. 60% of the children. The children＇s intakes of vitamin A had positive relations with IL-2, CD4^＋, IgG, CD4^＋/CD8^＋, and negative relation with IgM. The intakes of vitamin C had positive correlation with CD3^＋ CD4^＋/CD8^＋ , IgA, negative relation with IgM. The intakes vitamin E had positive relations with IL-2, CD4^＋, and IgG. Conclusion The children＇s intakes of vitamin A,C are inadequate.The intakes of vitamin A,C,E have correlations with levels on immune function.

关 键 词：学龄儿童 维生素A、C、E 膳食 免疫功能 

分 类 号：R153.2[医药卫生—营养与食品卫生学]