Perilipin对脂肪细胞内三酰甘油的代谢调控作用  

Metabolic Regulation Roles of Perilipin on Triglyceride in Adipocyte

作　　者：刘梅芳[1] 朱苏红[1] 王俊杰[1] 

机构地区：[1]济宁医学院生理学教研室,山东济宁272013

出　　处：《医学综述》2009年第17期2572-2575,共4页Medical Recapitulate

摘　　要：三酰甘油贮存在哺乳动物细胞内脂滴中,脂滴表面镶嵌着多种蛋白,对脂滴功能具有重要调节作用,因此脂滴也越来越多地被认为是一种代谢活跃的细胞器。新近的研究表明脂滴表面PAT家族蛋白perilipin对脂肪细胞内三酰甘油的代谢起全局性调控作用,本文就脂肪细胞内perilipin的功能予以综述。Triglycerides are stored in intracellular lipid droplets in mammalian cells, and there are many kinds of proteins located on the surface of lipid droplets, which play an important role in lipid droplets function,and thus lipid droplets are considered as active organelles in cells. Current evidences support that perilipin, a member of PAT family proteins, wholly regulates the metabolism of triglyceride in adipocytes. Here we reviewed the functions of perilipin in adipocytes.

关 键 词：PERILIPIN 脂滴 脂肪细胞 PAT家族蛋白 三酰甘油 

分 类 号：R331.3[医药卫生—人体生理学]