Discipline Key Special Project;Grant/Award Number:XKZDQY202001;Henan Provincial Key R&D and Promotion Special Project;Grant/Award Number:212102310033;Henan Provincial Medical Science and Technology Tackling Program;Grant/Award Number:LHGJ20220557;Key R&D Program of China;Grant/Award Number:2020YFC2006100,2020YFC2009000 and 2020YFC2009006;National Natural Science Foundation of China;Grant/Award Number:31471330 and 81870408。
Background:Nonalcoholic fatty liver disease(NAFLD)is one of the most common chronic liver diseases globally.Hepatic stellate cells(HSCs)are the major effector cells of liver fibrosis.HSCs contain abundant lipid drople...
Hepatitis B virus(HBV)infection poses a global health concern without a definitive cure;however,antiviral medications can effectively suppress viral replication.This study delves into the intricate interplay between l...
National Natural Science Foundation of China(81973376)。
Objective:To investigate the regulatory mechanism in liver fibrosis progression by nuclear receptor of farnesoid X receptor(FXR)and the lipid droplet-associated protein of perilipin 5(PLIN5).Methods:FXR response eleme...