氟西汀合并心理治疗对青少年抑郁症疗效的观察  

To study the curative effects of combined treatment in juvenile depression

作　　者：朱记军[1] 万清华 钱景华[3] 

机构地区：[1]东南大学医学院附属盐城医院神经内科,江苏盐城224001 [2]盐城心理卫生指导中心 [3]盐城师范学院附属文峰中学

出　　处：《中国民康医学》2009年第17期2135-2136,共2页Medical Journal of Chinese People’s Health

摘　　要：目的:探讨氟西汀合并个别心理治疗对青少年抑郁症的疗效。方法:将46例青少年抑郁症患者随机分为两组,氟西汀治疗组(药物组)、氟西汀合并个别心理治疗组(心疗组),并进行为期1年的观察,分别采用汉密尔顿抑郁量表(HAMD)、焦虑自评量表(SAS)和临床疗效总评量表(CGI)进行评定。结果:合并心理治疗组在治疗6周后HAMD、SAS、CGI-SI评分较单药治疗组差异有显著性(P<0.01),12周时两组的HAMD、SAS评分差异有显著性(P<0.01、0.05),1年末随访心疗组复发率低于药疗组(P<0.05)。结论:氟西汀合并心理治疗对青少年抑郁症的疗效优于单用氟西汀,起效快且复发率低,远期疗效好值得推广。Objective：To explore the curative effects and prognoses of fluoxetine combined with psychotherapy in the juvenile depression. Methods：46 patients with juvenile depression were randomly divided into psychotherapy group （treated with fluoxetine combined with psychotherapy） and drug group （with fluoxetine） for 6 and 12 weeks, and follow- up conducted after discharge for 1 year and curative effects assessed with the HAMD, SAS and CGI - SI. Results： There were significant differences in scores of both HAMD, SAS and CGI - SI of psychotherapy group than drug group at the end of 6 weeks （ P 〈 0.01 ）, and that of scores of HAMD and SAS of psychotherapy group than drug group at the end of 12 weeks （ P 〈 0.05 ）. Recurrent rate was lower in the psychotherapy group than drug group in 1 year （ P 〈 0.01 ）. Conclusions ： Combined therapy is better than single fluxetine in juvenile depression, which has the faster effects and lower recurrence rate, deserves spreading.

关 键 词：心理治疗 氟西汀 青少年 抑郁症 

分 类 号：R749.41[医药卫生—神经病学与精神病学]